HCSGD entry for APOBEC3G

1. General information

Official gene symbolAPOBEC3G
Entrez ID60489
Gene full nameapolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
Other gene symbolsA3G ARCD ARP-9 ARP9 CEM-15 CEM15 bK150C2.7 dJ494G10.1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000932Cytoplasmic mRNA processing bodyIDAcellular_component
GO:0002230Positive regulation of defense response to virus by hostIDAbiological_process
GO:0003723RNA bindingIDAmolecular_function
GO:0004126Cytidine deaminase activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005739MitochondrionIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0008270Zinc ion bindingIDAmolecular_function
GO:0009972Cytidine deaminationIDAbiological_process
GO:0010529Negative regulation of transpositionIDAbiological_process
GO:0016032Viral processTASbiological_process
GO:0016553Base conversion or substitution editingTASbiological_process
GO:0030529Ribonucleoprotein complexIDAcellular_component
GO:0030895Apolipoprotein B mRNA editing enzyme complexTAScellular_component
GO:0042803Protein homodimerization activityNASmolecular_function
GO:0045071Negative regulation of viral genome replicationIDAbiological_process
GO:0045087Innate immune responseIDAbiological_process
GO:0045869Negative regulation of single stranded viral RNA replication via double stranded DNA intermediateIDAbiological_process
GO:0047844Deoxycytidine deaminase activityIDAmolecular_function
GO:0048525Negative regulation of viral processIDAbiological_process
GO:0051607Defense response to virusIDAbiological_process
GO:0070383DNA cytosine deaminationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.91224693590.00762259030.99999024730.1744645217

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2394211056
GSE13712_SHEARDown-0.5659735150
GSE13712_STATICUp0.3830027418
GSE19018Down-0.0357972506
GSE19899_A1Down-0.3366933667
GSE19899_A2Down-0.9594165108
PubMed_21979375_A1Down-0.6105683183
PubMed_21979375_A2Down-0.8367063515
GSE35957Down-1.2096477499
GSE36640Down-0.2417128672
GSE54402Down-0.3464690574
GSE9593Down-0.0334358100
GSE43922Down-1.9954997715
GSE24585Up0.2426133386
GSE37065Up1.1828643596
GSE28863_A1Down-0.2106793716
GSE28863_A2Down-0.0704665697
GSE28863_A3Down-0.2173549351
GSE28863_A4Up0.2414335137
GSE48662Up0.0214088068

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.