HCSGD entry for RHO

1. General information

Official gene symbolRHO
Entrez ID6010
Gene full namerhodopsin
Other gene symbolsCSNBAD1 OPN2 RP4
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001523Retinoid metabolic processTASbiological_process
GO:0001750Photoreceptor outer segmentIDAcellular_component
GO:0001917Photoreceptor inner segmentIDAcellular_component
GO:0004930G-protein coupled receptor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005794Golgi apparatusIDAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006468Protein phosphorylationIEAbiological_process
GO:0007186G-protein coupled receptor signaling pathwayTASbiological_process
GO:0007601Visual perceptionIEAbiological_process
GO:0007603Phototransduction, visible lightTASbiological_process
GO:0009585Red, far-red light phototransductionIEAbiological_process
GO:0009881Photoreceptor activityIEAmolecular_function
GO:0016056Rhodopsin mediated signaling pathwayTASbiological_process
GO:0016918Retinal bindingIEAmolecular_function
GO:0018298Protein-chromophore linkageIEAbiological_process
GO:0022400Regulation of rhodopsin mediated signaling pathwayTASbiological_process
GO:0030867Rough endoplasmic reticulum membraneIEAcellular_component
GO:0042622Photoreceptor outer segment membraneIDAcellular_component
GO:0046872Metal ion bindingIEAmolecular_function
GO:0060041Retina development in camera-type eyeIEAbiological_process
GO:0060342Photoreceptor inner segment membraneIDAcellular_component
GO:0097381Photoreceptor disc membraneTAScellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.71190449450.84286944640.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0646718530
GSE13712_SHEARUp0.0801877095
GSE13712_STATICUp0.0451832160
GSE19018Up0.1297199802
GSE19899_A1Down-0.0009151739
GSE19899_A2Up0.1134017024
PubMed_21979375_A1Down-0.1016095704
PubMed_21979375_A2Down-0.1017436232
GSE35957Up0.2314773474
GSE36640Up0.0701266770
GSE54402Down-0.0099624953
GSE9593Up0.0162589347
GSE43922Up0.0133824986
GSE24585Up0.0660439369
GSE37065Down-0.0220265957
GSE28863_A1Up0.0579280346
GSE28863_A2Up0.0171165115
GSE28863_A3Up0.3253821347
GSE28863_A4Down-0.0614454941
GSE48662Down-0.0889614197

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

3-[Aminoethylphosphoryl]-[1,2-Di-Palmitoyl]-Sn-GlycerolDB01728 EXPT02544
PhosphonothreonineDB02482 EXPT03092
B-2-OctylglucosideDB03152 EXPT00687
HexadecanalDB03381 EXPT02611
Palmitic AcidDB03796 EXPT01393 | EXPT02607
Heptane-1,2,3-TriolDB04079 EXPT01791
Lauryl Dimethylamine-N-OxideDB04147 EXPT02013
(Hydroxyethyloxy)Tri(Ethyloxy)OctaneDB04233 EXPT00817
Heptyl 1-ThiohexopyranosideDB04450 EXPT01788
PhosphonoserineDB04522 EXPT02883

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.