HCSGD entry for RGS4
1. General information
| Official gene symbol | RGS4 |
|---|---|
| Entrez ID | 5999 |
| Gene full name | regulator of G-protein signaling 4 |
| Other gene symbols | RGP4 SCZD9 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000188 | Inactivation of MAPK activity | TAS | biological_process |
| GO:0001965 | G-protein alpha-subunit binding | IEA | molecular_function |
| GO:0005096 | GTPase activator activity | IBA | molecular_function |
| GO:0005516 | Calmodulin binding | TAS | molecular_function |
| GO:0005737 | Cytoplasm | IBA | cellular_component |
| GO:0005829 | Cytosol | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IBA | cellular_component |
| GO:0008277 | Regulation of G-protein coupled receptor protein signaling pathway | TAS | biological_process |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0038032 | Termination of G-protein coupled receptor signaling pathway | IEA | biological_process |
| GO:0043234 | Protein complex | IEA | cellular_component |
| GO:0043547 | Positive regulation of GTPase activity | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0037468219 | 0.0014465826 | 0.1640915282 | 0.0736470019 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0890955664 |
| GSE13712_SHEAR | Up | 1.4309844509 |
| GSE13712_STATIC | Up | 1.3321900860 |
| GSE19018 | Down | -0.8609225091 |
| GSE19899_A1 | Up | 0.5068140217 |
| GSE19899_A2 | Down | -0.8226418419 |
| PubMed_21979375_A1 | Down | -2.7041059070 |
| PubMed_21979375_A2 | Down | -3.2150504279 |
| GSE35957 | Up | 1.2989150510 |
| GSE36640 | Down | -1.6782333010 |
| GSE54402 | Up | 0.4678259892 |
| GSE9593 | Up | 4.0480125685 |
| GSE43922 | Down | -0.3108566732 |
| GSE24585 | Up | 0.6081824646 |
| GSE37065 | Down | -0.1952860164 |
| GSE28863_A1 | Down | -1.5067380190 |
| GSE28863_A2 | Up | 0.1433955860 |
| GSE28863_A3 | Down | -1.3037717009 |
| GSE28863_A4 | Up | 0.7651129774 |
| GSE48662 | Down | -0.3979967224 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
