HCSGD entry for RFX1
1. General information
| Official gene symbol | RFX1 |
|---|---|
| Entrez ID | 5989 |
| Gene full name | regulatory factor X, 1 (influences HLA class II expression) |
| Other gene symbols | EFC RFX |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003705 | RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006357 | Regulation of transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0006366 | Transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0006955 | Immune response | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4273014323 | 0.7934114585 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0006581606 |
| GSE13712_SHEAR | Up | 0.0170772698 |
| GSE13712_STATIC | Up | 0.1376160054 |
| GSE19018 | Up | 0.1497927416 |
| GSE19899_A1 | Up | 0.0101286048 |
| GSE19899_A2 | Up | 0.2086607532 |
| PubMed_21979375_A1 | Up | 0.0912326854 |
| PubMed_21979375_A2 | Up | 0.1165340984 |
| GSE35957 | Down | -0.1598409382 |
| GSE36640 | Down | -0.0953695752 |
| GSE54402 | Up | 0.1350650741 |
| GSE9593 | Down | -0.1071468144 |
| GSE43922 | Up | 0.0226912914 |
| GSE24585 | Down | -0.0231472624 |
| GSE37065 | Down | -0.0104198668 |
| GSE28863_A1 | Up | 0.1299085811 |
| GSE28863_A2 | Down | -0.3613004944 |
| GSE28863_A3 | Up | 0.2327324226 |
| GSE28863_A4 | Down | -0.0729976645 |
| GSE48662 | Up | 0.4378869993 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-197-3p | MIMAT0000227 | MIRT004209 | Microarray | Functional MTI (Weak) | 16822819 |
| hsa-miR-346 | MIMAT0000773 | MIRT004241 | Microarray | Functional MTI (Weak) | 16822819 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022998 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
