HCSGD entry for RFC2
1. General information
| Official gene symbol | RFC2 |
|---|---|
| Entrez ID | 5982 |
| Gene full name | replication factor C (activator 1) 2, 40kDa |
| Other gene symbols | A1 RFC40 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0000722 | Telomere maintenance via recombination | TAS | biological_process |
| GO:0000723 | Telomere maintenance | TAS | biological_process |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005663 | DNA replication factor C complex | IDA | cellular_component |
| GO:0006260 | DNA replication | IEA TAS | biological_process |
| GO:0006271 | DNA strand elongation involved in DNA replication | TAS | biological_process |
| GO:0006281 | DNA repair | TAS | biological_process |
| GO:0006283 | Transcription-coupled nucleotide-excision repair | TAS | biological_process |
| GO:0006289 | Nucleotide-excision repair | TAS | biological_process |
| GO:0006297 | Nucleotide-excision repair, DNA gap filling | TAS | biological_process |
| GO:0017111 | Nucleoside-triphosphatase activity | IEA | molecular_function |
| GO:0032201 | Telomere maintenance via semi-conservative replication | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9580527829 | 0.0036222750 | 0.9999902473 | 0.1224359435 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0993803162 |
| GSE13712_SHEAR | Down | -0.1046702193 |
| GSE13712_STATIC | Down | -0.0725554732 |
| GSE19018 | Down | -0.3779995040 |
| GSE19899_A1 | Down | -0.4235948520 |
| GSE19899_A2 | Down | -1.5411987002 |
| PubMed_21979375_A1 | Down | -0.8960004073 |
| PubMed_21979375_A2 | Down | -2.5768092251 |
| GSE35957 | Down | -1.0857726367 |
| GSE36640 | Down | -2.6895307149 |
| GSE54402 | Up | 0.2561010173 |
| GSE9593 | Down | -0.7226463677 |
| GSE43922 | Down | -0.5000900757 |
| GSE24585 | Up | 0.1126273177 |
| GSE37065 | Down | -0.1522478754 |
| GSE28863_A1 | Down | -0.1763552260 |
| GSE28863_A2 | Up | 0.8137501988 |
| GSE28863_A3 | Down | -0.0655844735 |
| GSE28863_A4 | Down | -0.0526497404 |
| GSE48662 | Down | -0.7435643514 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT023820 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045679 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-196a-5p | MIMAT0000226 | MIRT048154 | CLASH | Functional MTI (Weak) | 23622248 |
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