HCSGD entry for RDX


1. General information

Official gene symbolRDX
Entrez ID5962
Gene full nameradixin
Other gene symbolsDFNB24
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001726RuffleIEAcellular_component
GO:0003779Actin bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0005856CytoskeletonIEAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0005925Focal adhesionIDAcellular_component
GO:0008092Cytoskeletal protein bindingIEAmolecular_function
GO:0019898Extrinsic component of membraneIEAcellular_component
GO:0030027LamellipodiumIEAcellular_component
GO:0030033Microvillus assemblyIEAbiological_process
GO:0030175FilopodiumIEAcellular_component
GO:0030315T-tubuleIEAcellular_component
GO:0032154Cleavage furrowIEAcellular_component
GO:0032420StereociliumIEAcellular_component
GO:0045176Apical protein localizationIEAbiological_process
GO:0045177Apical part of cellIEAcellular_component
GO:0051286Cell tipIEAcellular_component
GO:0051693Actin filament cappingIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.98877567720.03125158240.99999024730.3315622733

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0495856966
GSE13712_SHEARDown-0.4649021156
GSE13712_STATICDown-0.8211900297
GSE19018Down-0.0512654406
GSE19899_A1Down-0.5109149318
GSE19899_A2Down-0.8753948347
PubMed_21979375_A1Down-0.5104300613
PubMed_21979375_A2Down-0.7624979850
GSE35957Down-0.0758471335
GSE36640Down-0.0559791198
GSE54402Down-0.1758511161
GSE9593Down-0.0300349236
GSE43922Down-0.4538015901
GSE24585Up0.1415764169
GSE37065Down-0.0382744404
GSE28863_A1Down-0.0158839396
GSE28863_A2Up0.0076324639
GSE28863_A3Up0.0715717069
GSE28863_A4Up0.0086001873
GSE48662Down-0.2379322367

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

D-Myo-Inositol-1,4,5-TriphosphateDB03401 EXPT01811

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-31-5pMIMAT0000089MIRT004979Luciferase reporter assay//qRT-PCR//Western blotFunctional MTI19524507
hsa-let-7b-5pMIMAT0000063MIRT032442ProteomicsFunctional MTI (Weak)18668040
hsa-miR-331-3pMIMAT0000760MIRT043310CLASHFunctional MTI (Weak)23622248
hsa-let-7e-5pMIMAT0000066MIRT051447CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.