HCSGD entry for RDH5


1. General information

Official gene symbolRDH5
Entrez ID5959
Gene full nameretinol dehydrogenase 5 (11-cis/9-cis)
Other gene symbols9cRDH HSD17B9 RDH1 SDR9C5
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001523Retinoid metabolic processTASbiological_process
GO:0004745Retinol dehydrogenase activityTASmolecular_function
GO:0005788Endoplasmic reticulum lumenIEAcellular_component
GO:0005789Endoplasmic reticulum membraneTAScellular_component
GO:0007601Visual perceptionIEAbiological_process
GO:0007603Phototransduction, visible lightTASbiological_process
GO:0016491Oxidoreductase activityIEAmolecular_function
GO:0042572Retinol metabolic processIEAbiological_process
GO:0044297Cell bodyIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.63497999700.46468101900.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0263710654
GSE13712_SHEARUp0.0538898236
GSE13712_STATICUp0.0244941943
GSE19018Down-0.1572878004
GSE19899_A1Down-0.0505071539
GSE19899_A2Down-0.0296842661
PubMed_21979375_A1Down-0.6615265887
PubMed_21979375_A2Down-0.3940932325
GSE35957Down-0.0643204210
GSE36640Up0.0578188556
GSE54402Down-0.0181224486
GSE9593Up0.5688611094
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.6342882388

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

NADHDB00157 NUTR00041 | DB01907 | EXPT02287 | DB03527
Vitamin ADB00162 NUTR00007 | APRD00486

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018312MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.