HCSGD entry for RBM4

1. General information

Official gene symbolRBM4
Entrez ID5936
Gene full nameRNA binding motif protein 4
Other gene symbolsLARK RBM4A ZCCHC21 ZCRB3A
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000166Nucleotide bindingIEAmolecular_function
GO:0000381Regulation of alternative mRNA splicing, via spliceosomeIDAbiological_process
GO:0002190Cap-independent translational initiationIDAbiological_process
GO:0002192IRES-dependent translational initiationIDAbiological_process
GO:0003676Nucleic acid bindingIEAmolecular_function
GO:0003723RNA bindingIDAmolecular_function
GO:0003729MRNA bindingIDAmolecular_function
GO:0003730MRNA 3'-UTR bindingISSmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005654NucleoplasmIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0006396RNA processingTASbiological_process
GO:0006397MRNA processingIEAbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0008380RNA splicingIEAbiological_process
GO:0010494Cytoplasmic stress granuleIDAcellular_component
GO:0016607Nuclear speckIDAcellular_component
GO:0017148Negative regulation of translationIDAbiological_process
GO:0030154Cell differentiationIEAbiological_process
GO:0032055Negative regulation of translation in response to stressIDAbiological_process
GO:0035198MiRNA bindingIDAmolecular_function
GO:0035278Negative regulation of translation involved in gene silencing by miRNAIDAbiological_process
GO:0043153Entrainment of circadian clock by photoperiodISSbiological_process
GO:0045947Negative regulation of translational initiationIDAbiological_process
GO:0046685Response to arsenic-containing substanceIDAbiological_process
GO:0046822Regulation of nucleocytoplasmic transportIDAbiological_process
GO:0051149Positive regulation of muscle cell differentiationIDAbiological_process
GO:0051403Stress-activated MAPK cascadeIDAbiological_process
GO:0097157Pre-mRNA intronic bindingIDAmolecular_function
GO:0097158Pre-mRNA intronic pyrimidine-rich bindingIDAmolecular_function
GO:0097167Circadian regulation of translationISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.09680347250.85811543250.65021531001.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0668003050
GSE13712_SHEARDown-0.0066260447
GSE13712_STATICUp0.4049227341
GSE19018Up0.2696781317
GSE19899_A1Down-0.0163082162
GSE19899_A2Up0.3753701567
PubMed_21979375_A1Down-0.2940087077
PubMed_21979375_A2Up1.2522858141
GSE35957Down-0.0195927632
GSE36640Up0.7641322774
GSE54402Down-0.1567606133
GSE9593Down-0.0562669678
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Up0.2524286611
GSE28863_A2Up0.1337034119
GSE28863_A3Down-0.5590047930
GSE28863_A4Up0.0802781132
GSE48662Up0.0037341105

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-197-3pMIMAT0000227MIRT004193MicroarrayFunctional MTI (Weak)16822819
hsa-let-7e-5pMIMAT0000066MIRT051520CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.