HCSGD entry for RXFP1
1. General information
| Official gene symbol | RXFP1 |
|---|---|
| Entrez ID | 59350 |
| Gene full name | relaxin/insulin-like family peptide receptor 1 |
| Other gene symbols | LGR7 RXFPR1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004930 | G-protein coupled receptor activity | IDA IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0007188 | Adenylate cyclase-modulating G-protein coupled receptor signaling pathway | IEA | biological_process |
| GO:0007567 | Parturition | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0030154 | Cell differentiation | IEA | biological_process |
| GO:0030198 | Extracellular matrix organization | IEA | biological_process |
| GO:0042562 | Hormone binding | IEA | molecular_function |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0060427 | Lung connective tissue development | IEA | biological_process |
| GO:0060658 | Nipple morphogenesis | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0218029482 | 0.5798802743 | 0.3550546125 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2013703016 |
| GSE13712_SHEAR | Up | 0.0261529182 |
| GSE13712_STATIC | Up | 0.0649491986 |
| GSE19018 | Up | 0.1462398691 |
| GSE19899_A1 | Down | -0.0638290311 |
| GSE19899_A2 | Up | 0.1483331743 |
| PubMed_21979375_A1 | Up | 0.2207895688 |
| PubMed_21979375_A2 | Up | 0.0464402361 |
| GSE35957 | Down | -0.0487314683 |
| GSE36640 | Up | 0.3140452618 |
| GSE54402 | Up | 0.0617731945 |
| GSE9593 | Up | 1.9746134279 |
| GSE43922 | Up | 0.0163942262 |
| GSE24585 | Down | -0.0090627187 |
| GSE37065 | Up | 0.2648889915 |
| GSE28863_A1 | Down | -1.1449925798 |
| GSE28863_A2 | Up | 3.3369927264 |
| GSE28863_A3 | Up | 0.4054726195 |
| GSE28863_A4 | Down | -0.0379549366 |
| GSE48662 | Up | 0.0273584407 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT023171 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-1 | MIMAT0000416 | MIRT024094 | Microarray | Functional MTI (Weak) | 18668037 |
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