HCSGD entry for RAP2B
1. General information
| Official gene symbol | RAP2B |
|---|---|
| Entrez ID | 5912 |
| Gene full name | RAP2B, member of RAS oncogene family |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003924 | GTPase activity | IEA | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005829 | Cytosol | IEA | cellular_component |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0019904 | Protein domain specific binding | IEA | molecular_function |
| GO:0030336 | Negative regulation of cell migration | IEA | biological_process |
| GO:0031954 | Positive regulation of protein autophosphorylation | IEA | biological_process |
| GO:0032486 | Rap protein signal transduction | ISS | biological_process |
| GO:0055038 | Recycling endosome membrane | ISS | cellular_component |
| GO:0061097 | Regulation of protein tyrosine kinase activity | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7516843091 | 0.1070900118 | 0.9999902473 | 0.6262856921 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3352872677 |
| GSE13712_SHEAR | Up | 0.2668949617 |
| GSE13712_STATIC | Up | 0.0715567386 |
| GSE19018 | Down | -0.0536612835 |
| GSE19899_A1 | Down | -0.0310809396 |
| GSE19899_A2 | Down | -0.4434580616 |
| PubMed_21979375_A1 | Down | -0.2769317355 |
| PubMed_21979375_A2 | Down | -0.6255689439 |
| GSE35957 | Down | -0.4388613919 |
| GSE36640 | Down | -0.5438610083 |
| GSE54402 | Up | 0.0770139790 |
| GSE9593 | Up | 0.1083853189 |
| GSE43922 | Down | -0.0376559631 |
| GSE24585 | Down | -0.3062427305 |
| GSE37065 | Down | -0.1697467900 |
| GSE28863_A1 | Up | 0.7164844528 |
| GSE28863_A2 | Down | -0.0834902179 |
| GSE28863_A3 | Down | -0.5801266041 |
| GSE28863_A4 | Up | 0.0152432941 |
| GSE48662 | Up | 0.0402901317 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-324-5p | MIMAT0000761 | MIRT043238 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-378a-5p | MIMAT0000731 | MIRT044000 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
