HCSGD entry for RANBP2
1. General information
| Official gene symbol | RANBP2 |
|---|---|
| Entrez ID | 5903 |
| Gene full name | RAN binding protein 2 |
| Other gene symbols | ANE1 IIAE3 NUP358 TRP1 TRP2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0003755 | Peptidyl-prolyl cis-trans isomerase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005643 | Nuclear pore | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005975 | Carbohydrate metabolic process | TAS | biological_process |
| GO:0006457 | Protein folding | IEA | biological_process |
| GO:0006606 | Protein import into nucleus | TAS | biological_process |
| GO:0007077 | Mitotic nuclear envelope disassembly | TAS | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0008536 | Ran GTPase binding | TAS | molecular_function |
| GO:0008645 | Hexose transport | TAS | biological_process |
| GO:0010827 | Regulation of glucose transport | TAS | biological_process |
| GO:0015758 | Glucose transport | TAS | biological_process |
| GO:0016032 | Viral process | TAS | biological_process |
| GO:0016874 | Ligase activity | IEA | molecular_function |
| GO:0016925 | Protein sumoylation | IDA IEA | biological_process |
| GO:0019221 | Cytokine-mediated signaling pathway | TAS | biological_process |
| GO:0031965 | Nuclear membrane | IDA | cellular_component |
| GO:0033132 | Negative regulation of glucokinase activity | IEA | biological_process |
| GO:0042405 | Nuclear inclusion body | IDA | cellular_component |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0044615 | Nuclear pore nuclear basket | IDA | cellular_component |
| GO:0051028 | MRNA transport | IEA | biological_process |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
| GO:0090526 | Regulation of gluconeogenesis involved in cellular glucose homeostasis | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6550064929 | 0.5286265036 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2499808030 |
| GSE13712_SHEAR | Down | -0.0244372440 |
| GSE13712_STATIC | Down | -0.0059383837 |
| GSE19018 | Down | -0.6046359806 |
| GSE19899_A1 | Up | 0.1787956474 |
| GSE19899_A2 | Down | -0.2295700045 |
| PubMed_21979375_A1 | Up | 0.0436936696 |
| PubMed_21979375_A2 | Up | 0.3460629931 |
| GSE35957 | Up | 0.4738846727 |
| GSE36640 | Down | -0.1698736322 |
| GSE54402 | Up | 0.0735082122 |
| GSE9593 | Down | -0.1922995639 |
| GSE43922 | Up | 0.0053788915 |
| GSE24585 | Up | 0.0126416874 |
| GSE37065 | Up | 0.0638683099 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.2004739474 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-708-5p | MIMAT0004926 | MIRT037743 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-106b-3p | MIMAT0004672 | MIRT038578 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-421 | MIMAT0003339 | MIRT039354 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-423-3p | MIMAT0001340 | MIRT042469 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045244 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125b-5p | MIMAT0000423 | MIRT046041 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7g-5p | MIMAT0000414 | MIRT046567 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049119 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051582 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052536 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
