HCSGD entry for RALGDS
1. General information
| Official gene symbol | RALGDS |
|---|---|
| Entrez ID | 5900 |
| Gene full name | ral guanine nucleotide dissociation stimulator |
| Other gene symbols | RGDS RGF RalGEF |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005083 | Small GTPase regulator activity | IDA NAS | molecular_function |
| GO:0005085 | Guanyl-nucleotide exchange factor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005622 | Intracellular | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0007264 | Small GTPase mediated signal transduction | IEA | biological_process |
| GO:0007265 | Ras protein signal transduction | TAS | biological_process |
| GO:0048011 | Neurotrophin TRK receptor signaling pathway | TAS | biological_process |
| GO:0050790 | Regulation of catalytic activity | IDA NAS | biological_process |
| GO:0051056 | Regulation of small GTPase mediated signal transduction | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0246064473 | 0.8166508947 | 0.3698202626 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0781984191 |
| GSE13712_SHEAR | Down | -0.3762722892 |
| GSE13712_STATIC | Down | -0.6553686475 |
| GSE19018 | Up | 0.1474634299 |
| GSE19899_A1 | Up | 0.4883444978 |
| GSE19899_A2 | Up | 1.1581902052 |
| PubMed_21979375_A1 | Up | 0.8041587636 |
| PubMed_21979375_A2 | Up | 1.4875600304 |
| GSE35957 | Down | -0.3692178175 |
| GSE36640 | Up | 0.3677203436 |
| GSE54402 | Up | 0.2547461081 |
| GSE9593 | Up | 0.3799837505 |
| GSE43922 | Up | 0.5445846701 |
| GSE24585 | Down | -0.3519453849 |
| GSE37065 | Down | -0.0885189482 |
| GSE28863_A1 | Down | -0.0698257819 |
| GSE28863_A2 | Up | 0.0460344969 |
| GSE28863_A3 | Up | 0.3086540074 |
| GSE28863_A4 | Down | -0.0678773457 |
| GSE48662 | Up | 0.7436894767 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017310 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039756 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT044953 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-183-5p | MIMAT0000261 | MIRT047157 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
