HCSGD entry for IL22RA1
1. General information
| Official gene symbol | IL22RA1 |
|---|---|
| Entrez ID | 58985 |
| Gene full name | interleukin 22 receptor, alpha 1 |
| Other gene symbols | CRF2-9 IL22R IL22R1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004904 | Interferon receptor activity | TAS | molecular_function |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0008150 | Biological_process | ND | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0019221 | Cytokine-mediated signaling pathway | TAS | biological_process |
| GO:0042015 | Interleukin-20 binding | IEA | molecular_function |
| GO:0050829 | Defense response to Gram-negative bacterium | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3632648950 | 0.8885328521 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1527344681 |
| GSE13712_SHEAR | Up | 0.1757928587 |
| GSE13712_STATIC | Down | -0.0766013919 |
| GSE19018 | Up | 0.0662707619 |
| GSE19899_A1 | Down | -0.0348331580 |
| GSE19899_A2 | Up | 0.0763164935 |
| PubMed_21979375_A1 | Down | -0.0128022273 |
| PubMed_21979375_A2 | Up | 0.2412662291 |
| GSE35957 | Up | 0.1235403687 |
| GSE36640 | Down | -0.0604078871 |
| GSE54402 | Down | -0.0995939672 |
| GSE9593 | Down | -0.2083033843 |
| GSE43922 | Up | 0.0261710552 |
| GSE24585 | Up | 0.1064554454 |
| GSE37065 | Up | 0.4144069770 |
| GSE28863_A1 | Down | -0.1179658673 |
| GSE28863_A2 | Up | 0.2125558420 |
| GSE28863_A3 | Up | 0.3057413895 |
| GSE28863_A4 | Up | 0.0660735177 |
| GSE48662 | Up | 0.0388611267 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029697 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 22473749 | IL-22R1 is generally thought to be expressed exclusively in epithelial cells |
| 22473749 | In this study, we identified high levels of IL-10R2 and IL-22R1 expression on hepatic stellate cells (HSCs), the predominant cell type involved in liver fibrogenesis in response to liver damage |
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