HCSGD entry for RABGGTB
1. General information
| Official gene symbol | RABGGTB |
|---|---|
| Entrez ID | 5876 |
| Gene full name | Rab geranylgeranyltransferase, beta subunit |
| Other gene symbols | GGTB |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004663 | Rab geranylgeranyltransferase activity | IEA ISS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005968 | Rab-protein geranylgeranyltransferase complex | ISS | cellular_component |
| GO:0006464 | Cellular protein modification process | NAS | biological_process |
| GO:0007601 | Visual perception | TAS | biological_process |
| GO:0008270 | Zinc ion binding | ISS | molecular_function |
| GO:0017137 | Rab GTPase binding | ISS | molecular_function |
| GO:0018344 | Protein geranylgeranylation | IEA ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9609659929 | 0.0239150298 | 0.9999902473 | 0.2981606433 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3281375523 |
| GSE13712_SHEAR | Down | -0.2996385636 |
| GSE13712_STATIC | Down | -0.0956896958 |
| GSE19018 | Down | -1.0131217103 |
| GSE19899_A1 | Down | -0.6572552289 |
| GSE19899_A2 | Down | -0.5702285567 |
| PubMed_21979375_A1 | Down | -0.4751830147 |
| PubMed_21979375_A2 | Down | -0.8693913049 |
| GSE35957 | Down | -0.1026766607 |
| GSE36640 | Down | -0.1251689632 |
| GSE54402 | Up | 0.2632684038 |
| GSE9593 | Up | 0.0212629187 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | Down | -0.1598350728 |
| GSE28863_A2 | Up | 0.1826448912 |
| GSE28863_A3 | Down | -0.3542224433 |
| GSE28863_A4 | Down | -0.1440527116 |
| GSE48662 | Down | -0.3648005415 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| N-Formylmethionine | DB04464 | EXPT01455 |
| FARNESYL DIPHOSPHATE | DB07780 | - |
| GERANYLGERANYL DIPHOSPHATE | DB07841 | - |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-98-5p | MIMAT0000096 | MIRT027619 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031743 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-1226-3p | MIMAT0005577 | MIRT036472 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041493 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049400 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
