HCSGD entry for RAB27B
1. General information
| Official gene symbol | RAB27B |
|---|---|
| Entrez ID | 5874 |
| Gene full name | RAB27B, member RAS oncogene family |
| Other gene symbols | C25KG |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003924 | GTPase activity | IEA ISS | molecular_function |
| GO:0005525 | GTP binding | IEA ISS | molecular_function |
| GO:0005794 | Golgi apparatus | IEA | cellular_component |
| GO:0005795 | Golgi stack | IDA | cellular_component |
| GO:0007264 | Small GTPase mediated signal transduction | IEA | biological_process |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0016324 | Apical plasma membrane | IEA | cellular_component |
| GO:0017157 | Regulation of exocytosis | IEA | biological_process |
| GO:0019003 | GDP binding | IDA | molecular_function |
| GO:0019904 | Protein domain specific binding | IPI | molecular_function |
| GO:0030140 | Trans-Golgi network transport vesicle | IDA | cellular_component |
| GO:0032585 | Multivesicular body membrane | IDA | cellular_component |
| GO:0042589 | Zymogen granule membrane | IEA | cellular_component |
| GO:0045921 | Positive regulation of exocytosis | IMP | biological_process |
| GO:0071985 | Multivesicular body sorting pathway | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0034268417 | 0.0867397211 | 0.1593602473 | 0.5591023506 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 2.2746836796 |
| GSE13712_SHEAR | Up | 0.0502749755 |
| GSE13712_STATIC | Down | -0.0139372227 |
| GSE19018 | Down | -0.1299991081 |
| GSE19899_A1 | Up | 0.1505596872 |
| GSE19899_A2 | Up | 0.6120183713 |
| PubMed_21979375_A1 | Up | 2.0225664378 |
| PubMed_21979375_A2 | Up | 1.8398404290 |
| GSE35957 | Down | -2.2473157413 |
| GSE36640 | Down | -0.0238210951 |
| GSE54402 | Up | 1.9579950333 |
| GSE9593 | Up | 1.1695527075 |
| GSE43922 | Up | 0.6876181562 |
| GSE24585 | Down | -0.7070713262 |
| GSE37065 | Up | 1.9006429471 |
| GSE28863_A1 | Down | -1.7076944113 |
| GSE28863_A2 | Up | 0.0485855002 |
| GSE28863_A3 | Down | -0.4577417355 |
| GSE28863_A4 | Down | -0.1041918124 |
| GSE48662 | Down | -0.1590618529 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT001512 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT005197 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-1 | MIMAT0000416 | MIRT023764 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
