HCSGD entry for RAB5B
1. General information
| Official gene symbol | RAB5B |
|---|---|
| Entrez ID | 5869 |
| Gene full name | RAB5B, member RAS oncogene family |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003924 | GTPase activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005622 | Intracellular | IDA | cellular_component |
| GO:0005768 | Endosome | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0006184 | GTP catabolic process | TAS | biological_process |
| GO:0007032 | Endosome organization | IEA | biological_process |
| GO:0007264 | Small GTPase mediated signal transduction | IEA | biological_process |
| GO:0008152 | Metabolic process | TAS | biological_process |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0016020 | Membrane | TAS | cellular_component |
| GO:0019003 | GDP binding | IDA | molecular_function |
| GO:0030100 | Regulation of endocytosis | IEA | biological_process |
| GO:0030139 | Endocytic vesicle | IEA | cellular_component |
| GO:0030742 | GTP-dependent protein binding | IDA | molecular_function |
| GO:0031901 | Early endosome membrane | IEA | cellular_component |
| GO:0042470 | Melanosome | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0166970632 | 0.9636766042 | 0.3190257620 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1892379050 |
| GSE13712_SHEAR | Up | 0.1187727749 |
| GSE13712_STATIC | Up | 0.0544934733 |
| GSE19018 | Up | 0.6848566562 |
| GSE19899_A1 | Up | 0.4007444746 |
| GSE19899_A2 | Up | 0.7378745374 |
| PubMed_21979375_A1 | Up | 0.2168784190 |
| PubMed_21979375_A2 | Up | 0.9278592162 |
| GSE35957 | Up | 0.3956361854 |
| GSE36640 | Up | 0.5022197791 |
| GSE54402 | Up | 0.2125644811 |
| GSE9593 | Up | 0.4310797615 |
| GSE43922 | Up | 0.0305134472 |
| GSE24585 | Up | 0.5194665916 |
| GSE37065 | Up | 0.0230820532 |
| GSE28863_A1 | Down | -0.0877902477 |
| GSE28863_A2 | Up | 0.0495106865 |
| GSE28863_A3 | Down | -0.6362716069 |
| GSE28863_A4 | Down | -0.0893502323 |
| GSE48662 | Up | 0.1900533115 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT016752 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-340-5p | MIMAT0004692 | MIRT019535 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-130b-3p | MIMAT0000691 | MIRT020119 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-96-5p | MIMAT0000095 | MIRT027918 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT027977 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-22-3p | MIMAT0000077 | MIRT030657 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031098 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-760 | MIMAT0004957 | MIRT036762 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT036953 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040223 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-23b-3p | MIMAT0000418 | MIRT046305 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-183-5p | MIMAT0000261 | MIRT047065 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-17-5p | MIMAT0000070 | MIRT050969 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7c-5p | MIMAT0000064 | MIRT051791 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
