HCSGD entry for QARS


1. General information

Official gene symbolQARS
Entrez ID5859
Gene full nameglutaminyl-tRNA synthetase
Other gene symbolsGLNRS PRO2195
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004812Aminoacyl-tRNA ligase activityIEAmolecular_function
GO:0004819Glutamine-tRNA ligase activityIEA TASmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005737CytoplasmIDA IEAcellular_component
GO:0005759Mitochondrial matrixTAScellular_component
GO:0005829CytosolTAScellular_component
GO:0006418TRNA aminoacylation for protein translationIEA TASbiological_process
GO:0006425Glutaminyl-tRNA aminoacylationIEAbiological_process
GO:0010467Gene expressionTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.99970821780.00706157060.99999024730.1677271827

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954--
GSE13712_SHEAR--
GSE13712_STATIC--
GSE19018--
GSE19899_A1--
GSE19899_A2--
PubMed_21979375_A1--
PubMed_21979375_A2--
GSE35957--
GSE36640--
GSE54402--
GSE9593--
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.4038056504

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029505MicroarrayFunctional MTI (Weak)19088304
hsa-let-7b-5pMIMAT0000063MIRT032373ProteomicsFunctional MTI (Weak)18668040
hsa-miR-744-5pMIMAT0004945MIRT037517CLASHFunctional MTI (Weak)23622248
hsa-miR-9-5pMIMAT0000441MIRT045782CLASHFunctional MTI (Weak)23622248
hsa-miR-15b-5pMIMAT0000417MIRT046503CLASHFunctional MTI (Weak)23622248
hsa-miR-17-5pMIMAT0000070MIRT050906CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.