HCSGD entry for SNX6


1. General information

Official gene symbolSNX6
Entrez ID58533
Gene full namesorting nexin 6
Other gene symbolsMSTP010 TFAF2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005622IntracellularNAScellular_component
GO:0005634NucleusIEAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0006886Intracellular protein transportIMP NASbiological_process
GO:0007154Cell communicationIEAbiological_process
GO:0007175Negative regulation of epidermal growth factor-activated receptor activityNASbiological_process
GO:0030512Negative regulation of transforming growth factor beta receptor signaling pathwayIDAbiological_process
GO:0030659Cytoplasmic vesicle membraneIEAcellular_component
GO:0031901Early endosome membraneIDAcellular_component
GO:0035091Phosphatidylinositol bindingIEAmolecular_function
GO:0042147Retrograde transport, endosome to GolgiIMPbiological_process
GO:0042803Protein homodimerization activityIPImolecular_function
GO:0043231Intracellular membrane-bounded organelleIDAcellular_component
GO:0045892Negative regulation of transcription, DNA-templatedIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.06465575780.94912516240.54853882091.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0732253017
GSE13712_SHEARUp0.2035900934
GSE13712_STATICUp0.3167509357
GSE19018Up0.4540056599
GSE19899_A1Up0.0699853328
GSE19899_A2Up0.3716238327
PubMed_21979375_A1Up0.6232519684
PubMed_21979375_A2Up0.5336172439
GSE35957Up0.2150639839
GSE36640Up0.4023640164
GSE54402Down-0.0746579869
GSE9593Up0.1980250581
GSE43922Down-0.0478569447
GSE24585Up0.4017655530
GSE37065Up0.2297731202
GSE28863_A1Up0.2195408219
GSE28863_A2Up0.0509862756
GSE28863_A3Up0.0044925552
GSE28863_A4Down-0.0621825623
GSE48662Down-0.3456530013

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1MIMAT0000416MIRT001331pSILAC//Proteomics;OtherFunctional MTI (Weak)18668040
hsa-miR-155-5pMIMAT0000646MIRT020606ProteomicsFunctional MTI (Weak)18668040
hsa-miR-16-5pMIMAT0000069MIRT031491ProteomicsFunctional MTI (Weak)18668040
hsa-miR-186-5pMIMAT0000456MIRT045044CLASHFunctional MTI (Weak)23622248
hsa-miR-15a-5pMIMAT0000068MIRT051325CLASHFunctional MTI (Weak)23622248
hsa-let-7a-5pMIMAT0000062MIRT052571CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.