HCSGD entry for ARHGAP22
1. General information
| Official gene symbol | ARHGAP22 |
|---|---|
| Entrez ID | 58504 |
| Gene full name | Rho GTPase activating protein 22 |
| Other gene symbols | RhoGAP2 RhoGap22 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001525 | Angiogenesis | IEA | biological_process |
| GO:0005096 | GTPase activator activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005622 | Intracellular | IEA | cellular_component |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0007165 | Signal transduction | IEA | biological_process |
| GO:0007264 | Small GTPase mediated signal transduction | TAS | biological_process |
| GO:0030154 | Cell differentiation | IEA | biological_process |
| GO:0051056 | Regulation of small GTPase mediated signal transduction | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0264924395 | 0.9373989172 | 0.3794719260 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4072156678 |
| GSE13712_SHEAR | Up | 0.3975146908 |
| GSE13712_STATIC | Up | 0.2296315001 |
| GSE19018 | Up | 0.1276329002 |
| GSE19899_A1 | Up | 0.4720751596 |
| GSE19899_A2 | Up | 0.8920056462 |
| PubMed_21979375_A1 | Up | 0.2975057634 |
| PubMed_21979375_A2 | Up | 0.0343802717 |
| GSE35957 | Down | -0.1903976120 |
| GSE36640 | Down | -0.0123581232 |
| GSE54402 | Up | 1.0339728594 |
| GSE9593 | Up | 0.5453870401 |
| GSE43922 | Up | 0.0207041731 |
| GSE24585 | Down | -0.5067858062 |
| GSE37065 | Up | 0.2045682633 |
| GSE28863_A1 | Down | -0.3394582568 |
| GSE28863_A2 | Up | 0.2110232801 |
| GSE28863_A3 | Up | 0.1691912111 |
| GSE28863_A4 | Up | 0.1541037410 |
| GSE48662 | Up | 0.0180954170 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022123 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039842 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
