HCSGD entry for JAM2
1. General information
| Official gene symbol | JAM2 |
|---|---|
| Entrez ID | 58494 |
| Gene full name | junctional adhesion molecule 2 |
| Other gene symbols | C21orf43 CD322 JAM-B JAMB PRO245 VE-JAM VEJAM |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | NAS | cellular_component |
| GO:0005923 | Tight junction | IEA | cellular_component |
| GO:0007162 | Negative regulation of cell adhesion | IEA | biological_process |
| GO:0007596 | Blood coagulation | TAS | biological_process |
| GO:0016337 | Cell-cell adhesion | NAS | biological_process |
| GO:0046982 | Protein heterodimerization activity | IEA | molecular_function |
| GO:0050900 | Leukocyte migration | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0963937730 | 0.0096966187 | 0.6491022222 | 0.1948280153 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.7099605900 |
| GSE13712_SHEAR | Down | -0.5908025141 |
| GSE13712_STATIC | Down | -0.5154082041 |
| GSE19018 | Down | -0.9418027470 |
| GSE19899_A1 | Up | 0.0531936729 |
| GSE19899_A2 | Down | -0.6821506383 |
| PubMed_21979375_A1 | Down | -0.2145786029 |
| PubMed_21979375_A2 | Down | -0.4647182403 |
| GSE35957 | Down | -0.1322590221 |
| GSE36640 | Down | -0.3853957010 |
| GSE54402 | Down | -0.3635771744 |
| GSE9593 | Down | -0.2560214914 |
| GSE43922 | Up | 0.1051303089 |
| GSE24585 | Up | 1.2465934982 |
| GSE37065 | Down | -0.1980015034 |
| GSE28863_A1 | Down | -0.9331449151 |
| GSE28863_A2 | Up | 0.9725714768 |
| GSE28863_A3 | Up | 0.7323574317 |
| GSE28863_A4 | Down | -0.0503763366 |
| GSE48662 | Up | 1.0003094026 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029914 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
