HCSGD entry for PLEKHB1
1. General information
| Official gene symbol | PLEKHB1 |
|---|---|
| Entrez ID | 58473 |
| Gene full name | pleckstrin homology domain containing, family B (evectins) member 1 |
| Other gene symbols | KPL1 PHR1 PHRET1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004871 | Signal transducer activity | TAS | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0007275 | Multicellular organismal development | IEA | biological_process |
| GO:0007602 | Phototransduction | NAS | biological_process |
| GO:0008022 | Protein C-terminus binding | IEA | molecular_function |
| GO:0016021 | Integral component of membrane | IDA | cellular_component |
| GO:0042803 | Protein homodimerization activity | IEA | molecular_function |
| GO:0045595 | Regulation of cell differentiation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6638545420 | 0.7622781163 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0040674102 |
| GSE13712_SHEAR | Down | -0.4249601987 |
| GSE13712_STATIC | Down | -0.0942668895 |
| GSE19018 | Up | 0.0754132754 |
| GSE19899_A1 | Up | 0.0574660529 |
| GSE19899_A2 | Up | 0.0211385208 |
| PubMed_21979375_A1 | Down | -0.1801710332 |
| PubMed_21979375_A2 | Down | -0.1550025159 |
| GSE35957 | Up | 0.0983857216 |
| GSE36640 | Down | -0.0635070349 |
| GSE54402 | Down | -0.0692168037 |
| GSE9593 | Up | 0.0496888998 |
| GSE43922 | Up | 0.1224263529 |
| GSE24585 | Up | 0.1022081211 |
| GSE37065 | Up | 0.0813792458 |
| GSE28863_A1 | Down | -0.0486979050 |
| GSE28863_A2 | Down | -0.1434413206 |
| GSE28863_A3 | Up | 0.4097219218 |
| GSE28863_A4 | Up | 0.1251636896 |
| GSE48662 | Up | 0.0723619387 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017412 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-9-5p | MIMAT0000441 | MIRT021332 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022411 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025679 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049007 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
