HCSGD entry for PYGB


1. General information

Official gene symbolPYGB
Entrez ID5834
Gene full namephosphorylase, glycogen; brain
Other gene symbolsGPBB
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005737CytoplasmIDAcellular_component
GO:0005975Carbohydrate metabolic processIEA TASbiological_process
GO:0005980Glycogen catabolic processNAS TASbiological_process
GO:0006006Glucose metabolic processTASbiological_process
GO:0008184Glycogen phosphorylase activityIEA NASmolecular_function
GO:0030170Pyridoxal phosphate bindingIEAmolecular_function
GO:0044281Small molecule metabolic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.10728060480.88596633870.68025362561.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0572940217
GSE13712_SHEARUp0.1422773986
GSE13712_STATICUp0.1153830312
GSE19018Up0.3884063961
GSE19899_A1Up0.2819579265
GSE19899_A2Down-0.2336218805
PubMed_21979375_A1Up0.2477194640
PubMed_21979375_A2Up0.4824270535
GSE35957Down-0.2577736114
GSE36640Up0.1314983118
GSE54402Up0.0383311020
GSE9593Up0.4956731897
GSE43922Down-0.0545990749
GSE24585Up0.1464905805
GSE37065Down-0.0492443532
GSE28863_A1Up0.1276700163
GSE28863_A2Up0.0339304107
GSE28863_A3Down-0.5922808875
GSE28863_A4Up0.2442167986
GSE48662Up0.3279441978

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017293MicroarrayFunctional MTI (Weak)18185580
hsa-miR-1MIMAT0000416MIRT023564ProteomicsFunctional MTI (Weak)18668040
hsa-miR-34a-5pMIMAT0000255MIRT025360ProteomicsFunctional MTI (Weak)21566225
hsa-miR-16-5pMIMAT0000069MIRT031538ProteomicsFunctional MTI (Weak)18668040
hsa-miR-744-5pMIMAT0004945MIRT037640CLASHFunctional MTI (Weak)23622248
hsa-miR-484MIMAT0002174MIRT042171CLASHFunctional MTI (Weak)23622248
hsa-miR-20a-5pMIMAT0000075MIRT050597CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.