HCSGD entry for PCYT2
1. General information
| Official gene symbol | PCYT2 |
|---|---|
| Entrez ID | 5833 |
| Gene full name | phosphate cytidylyltransferase 2, ethanolamine |
| Other gene symbols | ET |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003824 | Catalytic activity | IEA | molecular_function |
| GO:0004306 | Ethanolamine-phosphate cytidylyltransferase activity | IEA TAS | molecular_function |
| GO:0005575 | Cellular_component | ND | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0006644 | Phospholipid metabolic process | TAS | biological_process |
| GO:0006646 | Phosphatidylethanolamine biosynthetic process | IEA TAS | biological_process |
| GO:0008654 | Phospholipid biosynthetic process | TAS | biological_process |
| GO:0009058 | Biosynthetic process | IEA | biological_process |
| GO:0016779 | Nucleotidyltransferase activity | IEA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046474 | Glycerophospholipid biosynthetic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2148912921 | 0.3264431519 | 0.8928419416 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0845705427 |
| GSE13712_SHEAR | Up | 0.2125982323 |
| GSE13712_STATIC | Up | 0.1535857111 |
| GSE19018 | Down | -0.0444059506 |
| GSE19899_A1 | Down | -0.4201528127 |
| GSE19899_A2 | Up | 0.0849847588 |
| PubMed_21979375_A1 | Down | -0.0826401012 |
| PubMed_21979375_A2 | Up | 0.0158130153 |
| GSE35957 | Down | -0.0890778876 |
| GSE36640 | Up | 0.0197737298 |
| GSE54402 | Down | -0.0301067220 |
| GSE9593 | Up | 0.1253230206 |
| GSE43922 | Down | -0.8234341881 |
| GSE24585 | Up | 0.2547141302 |
| GSE37065 | Down | -0.3261517049 |
| GSE28863_A1 | Up | 0.3013721558 |
| GSE28863_A2 | Down | -0.2273044707 |
| GSE28863_A3 | Up | 0.7960788646 |
| GSE28863_A4 | Up | 0.0562579897 |
| GSE48662 | Up | 0.2517010061 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017368 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052191 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
