HCSGD entry for PEX2

1. General information

Official gene symbolPEX2
Entrez ID5828
Gene full nameperoxisomal biogenesis factor 2
Other gene symbolsPAF1 PBD5A PBD5B PMP3 PMP35 PXMP3 RNF72 ZWS3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000038Very long-chain fatty acid metabolic processIMPbiological_process
GO:0000122Negative regulation of transcription from RNA polymerase II promoterIMPbiological_process
GO:0001764Neuron migrationIEAbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005778Peroxisomal membraneIDA IEAcellular_component
GO:0005779Integral component of peroxisomal membraneIMPcellular_component
GO:0006635Fatty acid beta-oxidationIMPbiological_process
GO:0006699Bile acid biosynthetic processIEAbiological_process
GO:0007031Peroxisome organizationIMPbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0016558Protein import into peroxisome matrixIMPbiological_process
GO:0016593Cdc73/Paf1 complexIDAcellular_component
GO:0031648Protein destabilizationIMPbiological_process
GO:0042632Cholesterol homeostasisIEAbiological_process
GO:0045540Regulation of cholesterol biosynthetic processIEAbiological_process
GO:0048147Negative regulation of fibroblast proliferationIMPbiological_process
GO:0050680Negative regulation of epithelial cell proliferationIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.95761420160.04754239200.99999024730.4086751470

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0115883831
GSE13712_SHEARDown-0.5392003179
GSE13712_STATICDown-0.0791025953
GSE19018Up0.1551468510
GSE19899_A1Down-0.2945142702
GSE19899_A2Down-0.2746231099
PubMed_21979375_A1Down-0.7323546510
PubMed_21979375_A2Down-0.3914410813
GSE35957Up0.0877003146
GSE36640Up0.0375487933
GSE54402Down-0.4456182089
GSE9593Down-0.1113060310
GSE43922Down-0.4361640639
GSE24585Down-0.0807181890
GSE37065Up0.0285619372
GSE28863_A1Up0.4274408567
GSE28863_A2Down-0.1206649512
GSE28863_A3Down-0.4597268137
GSE28863_A4Down-0.0879505843
GSE48662Up0.0056097857

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.