HCSGD entry for PEX19
1. General information
| Official gene symbol | PEX19 |
|---|---|
| Entrez ID | 5824 |
| Gene full name | peroxisomal biogenesis factor 19 |
| Other gene symbols | D1S2223E HK33 PBD12A PMP1 PMPI PXF PXMP1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IMP | cellular_component |
| GO:0005737 | Cytoplasm | IDA IMP ISS | cellular_component |
| GO:0005777 | Peroxisome | IDA IEA ISS | cellular_component |
| GO:0005778 | Peroxisomal membrane | IDA | cellular_component |
| GO:0005829 | Cytosol | IDA TAS | cellular_component |
| GO:0006625 | Protein targeting to peroxisome | IDA IMP | biological_process |
| GO:0007031 | Peroxisome organization | IMP NAS | biological_process |
| GO:0016021 | Integral component of membrane | IDA | cellular_component |
| GO:0016557 | Peroxisome membrane biogenesis | IDA | biological_process |
| GO:0016559 | Peroxisome fission | IMP | biological_process |
| GO:0031526 | Brush border membrane | ISS | cellular_component |
| GO:0036105 | Peroxisome membrane class-1 targeting sequence binding | IDA | molecular_function |
| GO:0043234 | Protein complex | IDA | cellular_component |
| GO:0045046 | Protein import into peroxisome membrane | IDA | biological_process |
| GO:0047485 | Protein N-terminus binding | IPI | molecular_function |
| GO:0050821 | Protein stabilization | IDA | biological_process |
| GO:0051117 | ATPase binding | IPI | molecular_function |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
| GO:0061077 | Chaperone-mediated protein folding | IDA | biological_process |
| GO:0072321 | Chaperone-mediated protein transport | IDA | biological_process |
| GO:0072663 | Establishment of protein localization to peroxisome | IMP | biological_process |
| GO:1900131 | Negative regulation of lipid binding | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1931506668 | 0.8273046237 | 0.8521486255 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1477169804 |
| GSE13712_SHEAR | Down | -0.4649871616 |
| GSE13712_STATIC | Down | -0.1180476289 |
| GSE19018 | Up | 0.2699486910 |
| GSE19899_A1 | Down | -0.0079047854 |
| GSE19899_A2 | Up | 0.2924316893 |
| PubMed_21979375_A1 | Up | 0.2077142514 |
| PubMed_21979375_A2 | Up | 0.3222625578 |
| GSE35957 | Up | 0.3970122491 |
| GSE36640 | Up | 1.0608927734 |
| GSE54402 | Up | 0.0734607208 |
| GSE9593 | Up | 0.0098754511 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | Up | 0.0204379699 |
| GSE28863_A2 | Up | 0.3175974810 |
| GSE28863_A3 | Down | -0.5560104886 |
| GSE28863_A4 | Down | -0.2566219315 |
| GSE48662 | Up | 0.0216744452 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-221-3p | MIMAT0000278 | MIRT046878 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-31-5p | MIMAT0000089 | MIRT049884 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
