HCSGD entry for CTDSP1
1. General information
| Official gene symbol | CTDSP1 |
|---|---|
| Entrez ID | 58190 |
| Gene full name | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 |
| Other gene symbols | NIF3 NLI-IF NLIIF SCP1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA TAS | cellular_component |
| GO:0006357 | Regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0006470 | Protein dephosphorylation | IDA | biological_process |
| GO:0008420 | CTD phosphatase activity | IDA | molecular_function |
| GO:0016791 | Phosphatase activity | IEA | molecular_function |
| GO:0045665 | Negative regulation of neuron differentiation | IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0050768 | Negative regulation of neurogenesis | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9772284070 | 0.0128581475 | 0.9999902473 | 0.2238464026 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2761143529 |
| GSE13712_SHEAR | Down | -0.5137040641 |
| GSE13712_STATIC | Down | -0.7083759883 |
| GSE19018 | Down | -0.1766899370 |
| GSE19899_A1 | Down | -0.3806255958 |
| GSE19899_A2 | Down | -0.2837896135 |
| PubMed_21979375_A1 | Up | 0.1876686917 |
| PubMed_21979375_A2 | Down | -1.1396866520 |
| GSE35957 | Down | -0.4972719709 |
| GSE36640 | Down | -0.6218916523 |
| GSE54402 | Down | -0.2906833416 |
| GSE9593 | Down | -0.3986522092 |
| GSE43922 | Down | -0.1669869795 |
| GSE24585 | Up | 0.4737706011 |
| GSE37065 | Down | -0.1695883719 |
| GSE28863_A1 | Up | 0.2306694756 |
| GSE28863_A2 | Up | 0.1362241802 |
| GSE28863_A3 | Down | -0.3474915006 |
| GSE28863_A4 | Down | -0.3552794202 |
| GSE48662 | Up | 0.1376892065 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Aspartate Beryllium Trifluoride | DB04156 | EXPT00678 |
| Citric Acid | DB04272 | EXPT00922 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT002729 | Microarray | Functional MTI (Weak) | 15685193 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT002729 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT002729 | Reporter assay | Functional MTI | 17403776 |
| hsa-miR-128-3p | MIMAT0000424 | MIRT022103 | Reporter assay | Non-Functional MTI | 17403776 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025925 | Microarray | Functional MTI (Weak) | 19073608 |
| hsa-miR-24-3p | MIMAT0000080 | MIRT030562 | Microarray | Functional MTI (Weak) | 19748357 |
| hsa-miR-125b-5p | MIMAT0000423 | MIRT045998 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
