HCSGD entry for PVRL1

1. General information

Official gene symbolPVRL1
Entrez ID5818
Gene full namepoliovirus receptor-related 1 (herpesvirus entry mediator C)
Other gene symbolsCD111 CLPED1 ED4 HIgR HVEC OFC7 PRR PRR1 PVRR PVRR1 SK-12 nectin-1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001618Virus receptor activityIEAmolecular_function
GO:0002089Lens morphogenesis in camera-type eyeIEAbiological_process
GO:0002934Desmosome organizationIEAbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionIEAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005912Adherens junctionNAScellular_component
GO:0005913Cell-cell adherens junctionIDAcellular_component
GO:0006826Iron ion transportIEAbiological_process
GO:0006955Immune responseNASbiological_process
GO:0007155Cell adhesionNASbiological_process
GO:0007156Homophilic cell adhesionISSbiological_process
GO:0007157Heterophilic cell-cell adhesionISSbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007411Axon guidanceIEAbiological_process
GO:0015026Coreceptor activityTASmolecular_function
GO:0016020MembraneTAScellular_component
GO:0016021Integral component of membraneNAScellular_component
GO:0016337Cell-cell adhesionNASbiological_process
GO:0030246Carbohydrate bindingIEAmolecular_function
GO:0030424AxonIEAcellular_component
GO:0032584Growth cone membraneIEAcellular_component
GO:0034329Cell junction assemblyTASbiological_process
GO:0034332Adherens junction organizationTASbiological_process
GO:0042803Protein homodimerization activityISSmolecular_function
GO:0043231Intracellular membrane-bounded organelleIEAcellular_component
GO:0045202SynapseIEAcellular_component
GO:0045216Cell-cell junction organizationTASbiological_process
GO:0046718Viral entry into host cellNASbiological_process
GO:0046790Virion bindingIEAmolecular_function
GO:0046982Protein heterodimerization activityIEAmolecular_function
GO:0050839Cell adhesion molecule bindingIPImolecular_function
GO:0051963Regulation of synapse assemblyIEAbiological_process
GO:0060041Retina development in camera-type eyeIEAbiological_process
GO:0070166Enamel mineralizationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.56499567270.81586915390.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0429753534
GSE13712_SHEARDown-0.1814646985
GSE13712_STATICDown-0.0693210311
GSE19018Up0.1289389258
GSE19899_A1Up0.0462137391
GSE19899_A2Up0.1757860232
PubMed_21979375_A1Up0.4102424304
PubMed_21979375_A2Up0.0095199942
GSE35957Up0.1237681743
GSE36640Down-0.1899456023
GSE54402Up0.0327845915
GSE9593Down-0.0345709600
GSE43922Up0.1281037436
GSE24585Down-0.4046574430
GSE37065Up0.1127353061
GSE28863_A1Up0.1091476155
GSE28863_A2Up0.1018799503
GSE28863_A3Up0.2633736719
GSE28863_A4Up0.0397068119
GSE48662Down-0.1011827502

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-661MIMAT0003324MIRT004550immunoblot//qRT-PCRFunctional MTI (Weak)20543867
hsa-miR-615-3pMIMAT0003283MIRT039655CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.