HCSGD entry for PTX3
1. General information
| Official gene symbol | PTX3 |
|---|---|
| Entrez ID | 5806 |
| Gene full name | pentraxin 3, long |
| Other gene symbols | TNFAIP5 TSG-14 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001872 | (1->3)-beta-D-glucan binding | IEA | molecular_function |
| GO:0001878 | Response to yeast | IEA | biological_process |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0006954 | Inflammatory response | TAS | biological_process |
| GO:0008228 | Opsonization | IEA | biological_process |
| GO:0045429 | Positive regulation of nitric oxide biosynthetic process | IEA | biological_process |
| GO:0050766 | Positive regulation of phagocytosis | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0364394324 | 0.0180076061 | 0.4332829125 | 0.2627937396 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2690996716 |
| GSE13712_SHEAR | Up | 1.2045440557 |
| GSE13712_STATIC | Up | 0.2826577286 |
| GSE19018 | Down | -2.4301490740 |
| GSE19899_A1 | Down | -0.1515061978 |
| GSE19899_A2 | Up | 0.4276103408 |
| PubMed_21979375_A1 | Down | -2.7413656416 |
| PubMed_21979375_A2 | Down | -1.5714919143 |
| GSE35957 | Up | 0.5577662561 |
| GSE36640 | Up | 1.0410893342 |
| GSE54402 | Down | -0.6260039767 |
| GSE9593 | Up | 0.1334626733 |
| GSE43922 | Down | -0.8119052268 |
| GSE24585 | Up | 0.2837509930 |
| GSE37065 | Down | -0.7978930964 |
| GSE28863_A1 | Up | 0.2230052643 |
| GSE28863_A2 | Up | 1.2345326230 |
| GSE28863_A3 | Up | 0.1225465566 |
| GSE28863_A4 | Up | 0.3797692868 |
| GSE48662 | Up | 0.3069055701 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-21-5p | MIMAT0000076 | MIRT005954 | Luciferase reporter assay | Non-Functional MTI | 21131358 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
