HCSGD entry for PTPRZ1
1. General information
| Official gene symbol | PTPRZ1 |
|---|---|
| Entrez ID | 5803 |
| Gene full name | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 |
| Other gene symbols | HPTPZ HPTPzeta PTP-ZETA PTP18 PTPRZ PTPZ R-PTP-zeta-2 RPTPB RPTPbeta phosphacan |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004725 | Protein tyrosine phosphatase activity | IEA ISS | molecular_function |
| GO:0005001 | Transmembrane receptor protein tyrosine phosphatase activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005578 | Proteinaceous extracellular matrix | IEA | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0006470 | Protein dephosphorylation | TAS | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007409 | Axonogenesis | IEA | biological_process |
| GO:0007417 | Central nervous system development | TAS | biological_process |
| GO:0007611 | Learning or memory | ISS | biological_process |
| GO:0035335 | Peptidyl-tyrosine dephosphorylation | ISS | biological_process |
| GO:0048709 | Oligodendrocyte differentiation | ISS | biological_process |
| GO:0070445 | Regulation of oligodendrocyte progenitor proliferation | ISS | biological_process |
| GO:0072534 | Perineuronal net | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0114414194 | 0.9850168611 | 0.2705746631 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4503833243 |
| GSE13712_SHEAR | Up | 0.0080012355 |
| GSE13712_STATIC | Down | -0.1289091976 |
| GSE19018 | Up | 0.0428846982 |
| GSE19899_A1 | Up | 0.1361690585 |
| GSE19899_A2 | Up | 1.0260615824 |
| PubMed_21979375_A1 | Up | 0.2190732023 |
| PubMed_21979375_A2 | Up | 0.6230169285 |
| GSE35957 | Up | 0.8437295528 |
| GSE36640 | Up | 0.0759126886 |
| GSE54402 | Up | 2.1954698765 |
| GSE9593 | Down | -0.0195316069 |
| GSE43922 | Up | 0.0360327374 |
| GSE24585 | Up | 1.5721319337 |
| GSE37065 | Down | -0.0545187909 |
| GSE28863_A1 | Down | -0.0021207802 |
| GSE28863_A2 | Up | 0.1248619367 |
| GSE28863_A3 | Up | 0.0316045900 |
| GSE28863_A4 | Up | 0.0342807853 |
| GSE48662 | Down | -0.0388655354 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022444 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-181a-5p | MIMAT0000256 | MIRT025060 | Microarray | Functional MTI (Weak) | 17612493 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
