HCSGD entry for PTPRS


1. General information

Official gene symbolPTPRS
Entrez ID5802
Gene full nameprotein tyrosine phosphatase, receptor type, S
Other gene symbolsPTPSIGMA
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004725Protein tyrosine phosphatase activityIEAmolecular_function
GO:0005001Transmembrane receptor protein tyrosine phosphatase activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0007155Cell adhesionIEAbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0021510Spinal cord developmentIEAbiological_process
GO:0021549Cerebellum developmentIEAbiological_process
GO:0021766Hippocampus developmentIEAbiological_process
GO:0021987Cerebral cortex developmentIEAbiological_process
GO:0022038Corpus callosum developmentIEAbiological_process
GO:0030198Extracellular matrix organizationTASbiological_process
GO:0035335Peptidyl-tyrosine dephosphorylationTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.33498815770.23309944910.99999024730.9301714069

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0769033013
GSE13712_SHEARDown-0.5938781391
GSE13712_STATICDown-0.4313623536
GSE19018Up0.1667911227
GSE19899_A1Down-0.2009285193
GSE19899_A2Up0.0789120457
PubMed_21979375_A1Down-0.2742824086
PubMed_21979375_A2Down-0.2445588345
GSE35957Down-0.0952713118
GSE36640Up0.1030746610
GSE54402Down-0.0737515365
GSE9593Up0.0291815840
GSE43922Down-0.0680364209
GSE24585Down-0.0499780509
GSE37065Down-0.2981381967
GSE28863_A1Up1.5936157170
GSE28863_A2Up1.0478657073
GSE28863_A3Up0.1096480153
GSE28863_A4Down-0.0707810230
GSE48662Up0.0138686405

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Alendronic acidDB00630 APRD00561

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-20a-5pMIMAT0000075MIRT050574CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.