HCSGD entry for PTPRN2

1. General information

Official gene symbolPTPRN2
Entrez ID5799
Gene full nameprotein tyrosine phosphatase, receptor type, N polypeptide 2
Other gene symbolsIA-2beta IAR ICAAR PTPRP R-PTP-N2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004725Protein tyrosine phosphatase activityIEAmolecular_function
GO:0005001Transmembrane receptor protein tyrosine phosphatase activityTASmolecular_function
GO:0005788Endoplasmic reticulum lumenIEAcellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006470Protein dephosphorylationTASbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0030141Secretory granuleIEAcellular_component
GO:0030658Transport vesicle membraneIEAcellular_component
GO:0034260Negative regulation of GTPase activityIEAbiological_process
GO:0035335Peptidyl-tyrosine dephosphorylationTASbiological_process
GO:0043195Terminal boutonIEAcellular_component
GO:0043235Receptor complexIDAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.09769601080.89528661900.65329441201.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3565377770
GSE13712_SHEARDown-0.6027977644
GSE13712_STATICDown-0.5854983270
GSE19018Up0.1408904439
GSE19899_A1Up0.1622981842
GSE19899_A2Up1.0393262088
PubMed_21979375_A1Up0.3763599870
PubMed_21979375_A2Up0.6112619803
GSE35957Down-0.0734674770
GSE36640Down-0.0816324863
GSE54402Up0.2488904830
GSE9593Down-0.0321250220
GSE43922Up0.1928472869
GSE24585Up0.1679005365
GSE37065Down-0.0572701012
GSE28863_A1Up0.0000349507
GSE28863_A2Up0.1543934920
GSE28863_A3Up0.2772104695
GSE28863_A4Up0.1069058803
GSE48662Down-0.1345992820

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT002430Luciferase reporter assay//Microarray//Microarray;OtherFunctional MTI18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.