HCSGD entry for PTPRF
1. General information
| Official gene symbol | PTPRF |
|---|---|
| Entrez ID | 5792 |
| Gene full name | protein tyrosine phosphatase, receptor type, F |
| Other gene symbols | LAR |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004725 | Protein tyrosine phosphatase activity | IDA IEA | molecular_function |
| GO:0005001 | Transmembrane receptor protein tyrosine phosphatase activity | TAS | molecular_function |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0007155 | Cell adhesion | IEA | biological_process |
| GO:0007185 | Transmembrane receptor protein tyrosine phosphatase signaling pathway | TAS | biological_process |
| GO:0008201 | Heparin binding | IEA | molecular_function |
| GO:0035335 | Peptidyl-tyrosine dephosphorylation | IDA TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1890172980 | 0.0568346795 | 0.8469738338 | 0.4474859707 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.7793417227 |
| GSE13712_SHEAR | Up | 0.1714009617 |
| GSE13712_STATIC | Up | 0.1270433310 |
| GSE19018 | Up | 0.9268037815 |
| GSE19899_A1 | Down | -0.1391775696 |
| GSE19899_A2 | Down | -0.2026449423 |
| PubMed_21979375_A1 | Up | 0.3147053426 |
| PubMed_21979375_A2 | Down | -0.0085460708 |
| GSE35957 | Down | -0.2821449358 |
| GSE36640 | Down | -0.6396852722 |
| GSE54402 | Down | -0.6394838936 |
| GSE9593 | Up | 0.1066853705 |
| GSE43922 | Up | 0.0013788579 |
| GSE24585 | Down | -0.8401792171 |
| GSE37065 | Down | -0.1948129920 |
| GSE28863_A1 | Up | 0.4763164135 |
| GSE28863_A2 | Up | 0.9401466993 |
| GSE28863_A3 | Up | 0.2346773196 |
| GSE28863_A4 | Down | -0.1949793951 |
| GSE48662 | Up | 0.0677334091 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT001340 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-24-3p | MIMAT0000080 | MIRT035527 | Luciferase reporter assay | Functional MTI | 23418360 |
| hsa-miR-1914-5p | MIMAT0007889 | MIRT035797 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-1229-3p | MIMAT0005584 | MIRT036277 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-744-5p | MIMAT0004945 | MIRT037603 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-455-3p | MIMAT0004784 | MIRT037821 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-15b-3p | MIMAT0004586 | MIRT038659 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-221-3p | MIMAT0000278 | MIRT046964 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-1260b | MIMAT0015041 | MIRT052751 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
