HCSGD entry for PTPN13
1. General information
| Official gene symbol | PTPN13 |
|---|---|
| Entrez ID | 5783 |
| Gene full name | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) |
| Other gene symbols | FAP-1 PNP1 PTP-BAS PTP-BL PTP1E PTPL1 PTPLE hPTP1E |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004725 | Protein tyrosine phosphatase activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA IEA | cellular_component |
| GO:0005856 | Cytoskeleton | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006470 | Protein dephosphorylation | TAS | biological_process |
| GO:0030027 | Lamellipodium | IDA | cellular_component |
| GO:0035335 | Peptidyl-tyrosine dephosphorylation | IDA TAS | biological_process |
| GO:0043005 | Neuron projection | IEA | cellular_component |
| GO:0044297 | Cell body | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3547827552 | 0.0102274914 | 0.9999902473 | 0.2001470632 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3323809850 |
| GSE13712_SHEAR | Down | -0.7857789539 |
| GSE13712_STATIC | Down | -0.2903321926 |
| GSE19018 | Up | 0.1335795642 |
| GSE19899_A1 | Down | -0.2908974221 |
| GSE19899_A2 | Down | -0.2625215265 |
| PubMed_21979375_A1 | Down | -0.9936099246 |
| PubMed_21979375_A2 | Down | -0.4579894340 |
| GSE35957 | Down | -0.2729758960 |
| GSE36640 | Up | 0.7693511117 |
| GSE54402 | Down | -0.6016770696 |
| GSE9593 | Down | -0.8660258990 |
| GSE43922 | Down | -0.5739213850 |
| GSE24585 | Up | 0.4750539527 |
| GSE37065 | Down | -0.1156281289 |
| GSE28863_A1 | Up | 1.7525597157 |
| GSE28863_A2 | Up | 0.5657148510 |
| GSE28863_A3 | Up | 0.0499238129 |
| GSE28863_A4 | Down | -0.4932310417 |
| GSE48662 | Down | -0.2994997857 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-200c-3p | MIMAT0000617 | MIRT005593 | FACS//Luciferase reporter assay//qRT-PCR//Western blot//Reporter assay | Functional MTI | 20620960 |
| hsa-miR-194-5p | MIMAT0000460 | MIRT005894 | Luciferase reporter assay//qRT-PCR//Western blot | Functional MTI | 20979124 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043492 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045058 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049422 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
