HCSGD entry for RAP2C
1. General information
| Official gene symbol | RAP2C |
|---|---|
| Entrez ID | 57826 |
| Gene full name | RAP2C, member of RAS oncogene family |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003924 | GTPase activity | IEA | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005829 | Cytosol | IEA | cellular_component |
| GO:0030336 | Negative regulation of cell migration | ISS | biological_process |
| GO:0031954 | Positive regulation of protein autophosphorylation | ISS | biological_process |
| GO:0032486 | Rap protein signal transduction | ISS | biological_process |
| GO:0055038 | Recycling endosome membrane | ISS | cellular_component |
| GO:0061097 | Regulation of protein tyrosine kinase activity | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1967888910 | 0.5479326583 | 0.8583246811 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0424176489 |
| GSE13712_SHEAR | Up | 0.6988150457 |
| GSE13712_STATIC | Up | 0.2672695686 |
| GSE19018 | Up | 0.0084833233 |
| GSE19899_A1 | Up | 0.4354175449 |
| GSE19899_A2 | Down | -0.0654530771 |
| PubMed_21979375_A1 | Up | 0.6311583376 |
| PubMed_21979375_A2 | Up | 0.0028331898 |
| GSE35957 | Down | -0.3166026552 |
| GSE36640 | Down | -0.9844024896 |
| GSE54402 | Up | 0.4324275472 |
| GSE9593 | Down | -0.1648474584 |
| GSE43922 | Up | 0.2162770080 |
| GSE24585 | Down | -0.1285525345 |
| GSE37065 | Up | 0.0666315555 |
| GSE28863_A1 | Down | -0.0292526731 |
| GSE28863_A2 | Up | 0.0221815151 |
| GSE28863_A3 | Down | -0.1714820242 |
| GSE28863_A4 | Up | 0.1942960724 |
| GSE48662 | Down | -0.6903247007 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-423-3p | MIMAT0001340 | MIRT016688 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-375 | MIMAT0000728 | MIRT019855 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-130b-3p | MIMAT0000691 | MIRT020214 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-33a-5p | MIMAT0000091 | MIRT028204 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029388 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-24-3p | MIMAT0000080 | MIRT030453 | Microarray | Functional MTI (Weak) | 19748357 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031209 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032253 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-454-3p | MIMAT0003885 | MIRT039229 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-100-5p | MIMAT0000098 | MIRT048458 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
