HCSGD entry for HAMP


1. General information

Official gene symbolHAMP
Entrez ID57817
Gene full namehepcidin antimicrobial peptide
Other gene symbolsHEPC HFE2B LEAP1 PLTR
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005179Hormone activityIEAmolecular_function
GO:0005576Extracellular regionNAScellular_component
GO:0006879Cellular iron ion homeostasisIEAbiological_process
GO:0006955Immune responseTASbiological_process
GO:0031640Killing of cells of other organismIEAbiological_process
GO:0042742Defense response to bacteriumIEAbiological_process
GO:0045179Apical cortexIEAcellular_component
GO:0050832Defense response to fungusIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.31312311840.70413686030.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1194832930
GSE13712_SHEARUp0.1903908642
GSE13712_STATICUp0.2012973902
GSE19018Up0.1216453627
GSE19899_A1Up0.3586476643
GSE19899_A2Up0.1518267148
PubMed_21979375_A1Down-0.3614664366
PubMed_21979375_A2Down-0.0706274210
GSE35957Up0.1430461832
GSE36640Up0.1801617563
GSE54402Up0.0607522988
GSE9593Down-0.0004464364
GSE43922Up0.0881727335
GSE24585Down-0.0865611002
GSE37065Up0.0074957939
GSE28863_A1Down-0.0788750137
GSE28863_A2Down-0.0503657149
GSE28863_A3Up0.3191448681
GSE28863_A4Down-0.2023806643
GSE48662Down-0.2682726024

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.