HCSGD entry for KIAA1967
1. General information
| Official gene symbol | KIAA1967 |
|---|---|
| Entrez ID | 57805 |
| Gene full name | KIAA1967 |
| Other gene symbols | DBC-1 DBC1 NET35 p30 DBC p30DBC |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000790 | Nuclear chromatin | IDA | cellular_component |
| GO:0000993 | RNA polymerase II core binding | IDA | molecular_function |
| GO:0004857 | Enzyme inhibitor activity | IDA IMP | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005681 | Spliceosomal complex | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005759 | Mitochondrial matrix | IDA | cellular_component |
| GO:0006397 | MRNA processing | IEA | biological_process |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0006974 | Cellular response to DNA damage stimulus | IEA | biological_process |
| GO:0007049 | Cell cycle | IEA | biological_process |
| GO:0008380 | RNA splicing | IMP | biological_process |
| GO:0009411 | Response to UV | IMP | biological_process |
| GO:0019899 | Enzyme binding | IPI | molecular_function |
| GO:0032784 | Regulation of DNA-templated transcription, elongation | IMP | biological_process |
| GO:0043065 | Positive regulation of apoptotic process | IMP | biological_process |
| GO:0043086 | Negative regulation of catalytic activity | IDA IMP | biological_process |
| GO:0043653 | Mitochondrial fragmentation involved in apoptotic process | IDA | biological_process |
| GO:0044609 | DBIRD complex | IDA | cellular_component |
| GO:0050790 | Regulation of catalytic activity | IDA IMP | biological_process |
| GO:1902230 | Negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage | IMP | biological_process |
| GO:2000003 | Positive regulation of DNA damage checkpoint | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8880984461 | 0.2212807834 | 0.9999902473 | 0.9050323132 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1133802199 |
| GSE13712_SHEAR | Down | -0.1081541706 |
| GSE13712_STATIC | Down | -0.2309544084 |
| GSE19018 | Down | -0.0867459463 |
| GSE19899_A1 | Down | -0.0830118999 |
| GSE19899_A2 | Down | -0.0933476456 |
| PubMed_21979375_A1 | Down | -0.4119737550 |
| PubMed_21979375_A2 | Up | 0.0191018528 |
| GSE35957 | Down | -0.1180921665 |
| GSE36640 | Down | -0.6609064969 |
| GSE54402 | Down | -0.0144482243 |
| GSE9593 | Down | -0.2050557568 |
| GSE43922 | Up | 0.0951586273 |
| GSE24585 | Down | -0.0712062666 |
| GSE37065 | Down | -0.1988695644 |
| GSE28863_A1 | Up | 0.4295254751 |
| GSE28863_A2 | Down | -0.1574455232 |
| GSE28863_A3 | Down | -0.0541811570 |
| GSE28863_A4 | Down | -0.0093860563 |
| GSE48662 | Up | 0.1397180410 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT023212 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-24-3p | MIMAT0000080 | MIRT030599 | Microarray | Functional MTI (Weak) | 19748357 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031225 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-760 | MIMAT0004957 | MIRT036741 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT037197 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039823 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045623 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
