HCSGD entry for POLD4

1. General information

Official gene symbolPOLD4
Entrez ID57804
Gene full namepolymerase (DNA-directed), delta 4, accessory subunit
Other gene symbolsPOLDS p12
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000278Mitotic cell cycleTASbiological_process
GO:0000722Telomere maintenance via recombinationTASbiological_process
GO:0000723Telomere maintenanceTASbiological_process
GO:0001938Positive regulation of endothelial cell proliferationIEAbiological_process
GO:0003887DNA-directed DNA polymerase activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIEA TAScellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0006260DNA replicationIEA TASbiological_process
GO:0006271DNA strand elongation involved in DNA replicationTASbiological_process
GO:0006281DNA repairTASbiological_process
GO:0006283Transcription-coupled nucleotide-excision repairTASbiological_process
GO:0006284Base-excision repairTASbiological_process
GO:0006289Nucleotide-excision repairTASbiological_process
GO:0006297Nucleotide-excision repair, DNA gap fillingTASbiological_process
GO:0032201Telomere maintenance via semi-conservative replicationTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.29481014780.55114605830.99419979511.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0540197234
GSE13712_SHEARDown-0.2008992613
GSE13712_STATICUp0.0602501792
GSE19018Up0.3231691503
GSE19899_A1Up0.2335969613
GSE19899_A2Up0.0965821678
PubMed_21979375_A1Up0.1402931274
PubMed_21979375_A2Up0.4202791547
GSE35957Down-0.7754467041
GSE36640Up0.2907350656
GSE54402Up0.2266911703
GSE9593Down-0.1147644725
GSE43922Up0.2002375786
GSE24585Up0.2200228767
GSE37065Down-0.1981554218
GSE28863_A1Down-0.0392513905
GSE28863_A2Down-0.2555018877
GSE28863_A3Down-0.0600476609
GSE28863_A4Up0.0317081657
GSE48662Down-0.1437255333

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017868MicroarrayFunctional MTI (Weak)18185580
hsa-miR-26b-5pMIMAT0000083MIRT029515MicroarrayFunctional MTI (Weak)19088304
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.