HCSGD entry for PTPN9


1. General information

Official gene symbolPTPN9
Entrez ID5780
Gene full nameprotein tyrosine phosphatase, non-receptor type 9
Other gene symbolsMEG2 PTPMEG2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004725Protein tyrosine phosphatase activityIDAmolecular_function
GO:0004726Non-membrane spanning protein tyrosine phosphatase activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0006470Protein dephosphorylationTASbiological_process
GO:0035335Peptidyl-tyrosine dephosphorylationIDA TASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.69993547740.62195511950.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0332189463
GSE13712_SHEARUp0.1005974843
GSE13712_STATICDown-0.1541747605
GSE19018Down-0.2177287891
GSE19899_A1Down-0.1543398401
GSE19899_A2Down-0.0471264611
PubMed_21979375_A1Up0.4325651476
PubMed_21979375_A2Up0.1964625272
GSE35957Up0.0652445430
GSE36640Down-0.3439798727
GSE54402Up0.1975454880
GSE9593Up0.0962896604
GSE43922Down-0.0122738888
GSE24585Up0.0898178399
GSE37065Up0.0512914639
GSE28863_A1Up0.1766871949
GSE28863_A2Down-0.0258694152
GSE28863_A3Down-0.0895906085
GSE28863_A4Down-0.0704614978
GSE48662Up0.1318648070

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-769-5pMIMAT0003886MIRT016099SequencingFunctional MTI (Weak)20371350
hsa-miR-186-5pMIMAT0000456MIRT021174SequencingFunctional MTI (Weak)20371350
hsa-miR-124-3pMIMAT0000422MIRT023053MicroarrayFunctional MTI (Weak)18668037
hsa-miR-24-3pMIMAT0000080MIRT035526Luciferase reporter assayFunctional MTI23418360
hsa-miR-93-3pMIMAT0004509MIRT038760CLASHFunctional MTI (Weak)23622248
hsa-miR-320aMIMAT0000510MIRT044505CLASHFunctional MTI (Weak)23622248
hsa-miR-183-5pMIMAT0000261MIRT047068CLASHFunctional MTI (Weak)23622248
hsa-miR-100-5pMIMAT0000098MIRT048461CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.