HCSGD entry for PTPN7
1. General information
| Official gene symbol | PTPN7 |
|---|---|
| Entrez ID | 5778 |
| Gene full name | protein tyrosine phosphatase, non-receptor type 7 |
| Other gene symbols | BPTP-4 HEPTP LC-PTP LPTP PTPNI |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004725 | Protein tyrosine phosphatase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | IDA IEA | cellular_component |
| GO:0005856 | Cytoskeleton | IEA | cellular_component |
| GO:0006470 | Protein dephosphorylation | TAS | biological_process |
| GO:0009898 | Cytoplasmic side of plasma membrane | IDA | cellular_component |
| GO:0035335 | Peptidyl-tyrosine dephosphorylation | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5147947000 | 0.8455431557 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0225132305 |
| GSE13712_SHEAR | Up | 0.2196301464 |
| GSE13712_STATIC | Down | -0.2236951823 |
| GSE19018 | Up | 0.1444051832 |
| GSE19899_A1 | Up | 0.1104353764 |
| GSE19899_A2 | Up | 0.0240375064 |
| PubMed_21979375_A1 | Up | 0.2175597133 |
| PubMed_21979375_A2 | Up | 0.0263097574 |
| GSE35957 | Up | 0.0959207024 |
| GSE36640 | Down | -0.0814800117 |
| GSE54402 | Up | 0.0274986453 |
| GSE9593 | Up | 0.0743534086 |
| GSE43922 | Up | 0.0164476167 |
| GSE24585 | Up | 0.0824309034 |
| GSE37065 | Up | 0.0041613988 |
| GSE28863_A1 | Down | -0.3231981917 |
| GSE28863_A2 | Down | -0.1983682494 |
| GSE28863_A3 | Up | 0.3962765693 |
| GSE28863_A4 | Up | 0.1953650969 |
| GSE48662 | Down | -0.0010324126 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-126-3p | MIMAT0000445 | MIRT005727 | Flow//Immunoprecipitaion//Luciferase reporter assay//qRT-PCR//Western blot | Functional MTI | 21163928 |
| hsa-miR-126-5p | MIMAT0000444 | MIRT005728 | Flow//Immunoprecipitaion//Luciferase reporter assay//qRT-PCR//Western blot | Functional MTI | 21163928 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT018524 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
