HCSGD entry for ZFYVE28
1. General information
| Official gene symbol | ZFYVE28 |
|---|---|
| Entrez ID | 57732 |
| Gene full name | zinc finger, FYVE domain containing 28 |
| Other gene symbols | LST2 LYST2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005829 | Cytosol | IDA | cellular_component |
| GO:0007175 | Negative regulation of epidermal growth factor-activated receptor activity | IMP | biological_process |
| GO:0031901 | Early endosome membrane | IDA | cellular_component |
| GO:0032266 | Phosphatidylinositol-3-phosphate binding | IDA | molecular_function |
| GO:0042059 | Negative regulation of epidermal growth factor receptor signaling pathway | IMP | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1213154135 | 0.9553301888 | 0.7122781619 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0991518512 |
| GSE13712_SHEAR | Up | 0.8165633692 |
| GSE13712_STATIC | Up | 0.6356598894 |
| GSE19018 | Up | 0.0441170698 |
| GSE19899_A1 | Up | 0.1388319331 |
| GSE19899_A2 | Up | 0.7990596290 |
| PubMed_21979375_A1 | Up | 0.1702830371 |
| PubMed_21979375_A2 | Up | 0.3134691773 |
| GSE35957 | Down | -0.0869537687 |
| GSE36640 | Up | 0.0055864200 |
| GSE54402 | Up | 0.1961577647 |
| GSE9593 | Up | 0.1623584364 |
| GSE43922 | Up | 0.0257082898 |
| GSE24585 | Down | -0.1078724894 |
| GSE37065 | Up | 0.0643623510 |
| GSE28863_A1 | Down | -0.1507605759 |
| GSE28863_A2 | Up | 0.0115854147 |
| GSE28863_A3 | Up | 0.1062291827 |
| GSE28863_A4 | Down | -0.0557784279 |
| GSE48662 | Down | -0.0599750916 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018096 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026573 | Microarray | Functional MTI (Weak) | 19074876 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
