HCSGD entry for MIER1
1. General information
| Official gene symbol | MIER1 |
|---|---|
| Entrez ID | 57708 |
| Gene full name | mesoderm induction early response 1 homolog (Xenopus laevis) |
| Other gene symbols | ER1 MI-ER1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003682 | Chromatin binding | IEA | molecular_function |
| GO:0004871 | Signal transducer activity | IMP | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0007165 | Signal transduction | IMP | biological_process |
| GO:0017053 | Transcriptional repressor complex | IDA | cellular_component |
| GO:0031937 | Positive regulation of chromatin silencing | IDA | biological_process |
| GO:0043123 | Positive regulation of I-kappaB kinase/NF-kappaB signaling | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1255248889 | 0.9475797044 | 0.7226858392 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0238845621 |
| GSE13712_SHEAR | Up | 0.2045398561 |
| GSE13712_STATIC | Up | 0.2820975304 |
| GSE19018 | Up | 0.0484854215 |
| GSE19899_A1 | Up | 0.1700534359 |
| GSE19899_A2 | Down | -0.2305218366 |
| PubMed_21979375_A1 | Up | 0.0633609393 |
| PubMed_21979375_A2 | Up | 0.1131830671 |
| GSE35957 | Up | 0.0161757528 |
| GSE36640 | Down | -0.1221084130 |
| GSE54402 | Up | 0.0988996550 |
| GSE9593 | Up | 0.1226197087 |
| GSE43922 | Down | -0.0395368287 |
| GSE24585 | Up | 0.3788484083 |
| GSE37065 | Up | 0.2969776356 |
| GSE28863_A1 | Up | 0.4083235756 |
| GSE28863_A2 | Up | 0.5985140123 |
| GSE28863_A3 | Down | -0.0951816722 |
| GSE28863_A4 | Up | 0.0056454749 |
| GSE48662 | Up | 0.1982484560 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT024096 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-30e-5p | MIMAT0000692 | MIRT044128 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
