HCSGD entry for DENND1A
1. General information
| Official gene symbol | DENND1A |
|---|---|
| Entrez ID | 57706 |
| Gene full name | DENN/MADD domain containing 1A |
| Other gene symbols | FAM31A KIAA1608 RP11-230L22.3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0006897 | Endocytosis | IMP | biological_process |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0017112 | Rab guanyl-nucleotide exchange factor activity | IDA | molecular_function |
| GO:0017124 | SH3 domain binding | IEA | molecular_function |
| GO:0030054 | Cell junction | IEA | cellular_component |
| GO:0030136 | Clathrin-coated vesicle | IDA | cellular_component |
| GO:0030425 | Dendrite | IEA | cellular_component |
| GO:0030665 | Clathrin-coated vesicle membrane | IEA | cellular_component |
| GO:0032313 | Regulation of Rab GTPase activity | IDA | biological_process |
| GO:0032318 | Regulation of Ras GTPase activity | IDA | biological_process |
| GO:0032483 | Regulation of Rab protein signal transduction | IDA | biological_process |
| GO:0042734 | Presynaptic membrane | IEA | cellular_component |
| GO:0043025 | Neuronal cell body | IEA | cellular_component |
| GO:0043087 | Regulation of GTPase activity | IDA | biological_process |
| GO:0048488 | Synaptic vesicle endocytosis | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1697913111 | 0.7833438433 | 0.8112320022 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1008549795 |
| GSE13712_SHEAR | Down | -0.0252537917 |
| GSE13712_STATIC | Up | 0.2315158397 |
| GSE19018 | Up | 0.1889846605 |
| GSE19899_A1 | Down | -0.0721685516 |
| GSE19899_A2 | Down | -0.0861998278 |
| PubMed_21979375_A1 | Up | 0.6474521433 |
| PubMed_21979375_A2 | Up | 0.3474821294 |
| GSE35957 | Down | -0.0936592790 |
| GSE36640 | Down | -0.6711018144 |
| GSE54402 | Up | 0.2630077387 |
| GSE9593 | Down | -0.2422463816 |
| GSE43922 | Up | 0.0303764712 |
| GSE24585 | Up | 0.0742288103 |
| GSE37065 | Up | 0.2533348853 |
| GSE28863_A1 | Up | 0.1501931552 |
| GSE28863_A2 | Up | 0.1064756151 |
| GSE28863_A3 | Down | -0.0254528841 |
| GSE28863_A4 | Up | 0.1044021986 |
| GSE48662 | Down | -0.0066891512 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-192-5p | MIMAT0000222 | MIRT026656 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027739 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
