HCSGD entry for USP37
1. General information
| Official gene symbol | USP37 |
|---|---|
| Entrez ID | 57695 |
| Gene full name | ubiquitin specific peptidase 37 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000082 | G1/S transition of mitotic cell cycle | IDA | biological_process |
| GO:0004197 | Cysteine-type endopeptidase activity | IDA | molecular_function |
| GO:0004221 | Ubiquitin thiolesterase activity | IEA | molecular_function |
| GO:0004843 | Ubiquitin-specific protease activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0006511 | Ubiquitin-dependent protein catabolic process | IEA | biological_process |
| GO:0007067 | Mitosis | IEA | biological_process |
| GO:0019901 | Protein kinase binding | IPI | molecular_function |
| GO:0035871 | Protein K11-linked deubiquitination | IDA | biological_process |
| GO:0071108 | Protein K48-linked deubiquitination | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9583123058 | 0.0087804681 | 0.9999902473 | 0.1864568090 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2431232610 |
| GSE13712_SHEAR | Up | 0.0249882124 |
| GSE13712_STATIC | Down | -0.1683687593 |
| GSE19018 | Down | -0.1596379846 |
| GSE19899_A1 | Down | -0.0687552625 |
| GSE19899_A2 | Down | -1.3014965757 |
| PubMed_21979375_A1 | Down | -0.2074330926 |
| PubMed_21979375_A2 | Down | -1.0454672788 |
| GSE35957 | Down | -0.9341302634 |
| GSE36640 | Down | -1.4781073893 |
| GSE54402 | Up | 0.2118197651 |
| GSE9593 | Down | -0.0712103839 |
| GSE43922 | Down | -0.4619662935 |
| GSE24585 | Up | 0.4257938241 |
| GSE37065 | Up | 0.2153602267 |
| GSE28863_A1 | Down | -0.1298342548 |
| GSE28863_A2 | Up | 0.5864770968 |
| GSE28863_A3 | Down | -0.9577401432 |
| GSE28863_A4 | Down | -0.4367880958 |
| GSE48662 | Down | -0.2180139526 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031252 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-30c-5p | MIMAT0000244 | MIRT047922 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051589 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
