HCSGD entry for GPAM
1. General information
| Official gene symbol | GPAM |
|---|---|
| Entrez ID | 57678 |
| Gene full name | glycerol-3-phosphate acyltransferase, mitochondrial |
| Other gene symbols | GPAT GPAT1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004366 | Glycerol-3-phosphate O-acyltransferase activity | IEA IMP | molecular_function |
| GO:0005741 | Mitochondrial outer membrane | TAS | cellular_component |
| GO:0005743 | Mitochondrial inner membrane | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0006631 | Fatty acid metabolic process | IEA | biological_process |
| GO:0006637 | Acyl-CoA metabolic process | IEA | biological_process |
| GO:0006644 | Phospholipid metabolic process | TAS | biological_process |
| GO:0006654 | Phosphatidic acid biosynthetic process | TAS | biological_process |
| GO:0008654 | Phospholipid biosynthetic process | IEA | biological_process |
| GO:0009749 | Response to glucose | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016024 | CDP-diacylglycerol biosynthetic process | IEA | biological_process |
| GO:0019432 | Triglyceride biosynthetic process | IDA TAS | biological_process |
| GO:0040018 | Positive regulation of multicellular organism growth | IEA | biological_process |
| GO:0042104 | Positive regulation of activated T cell proliferation | IEA | biological_process |
| GO:0044255 | Cellular lipid metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046474 | Glycerophospholipid biosynthetic process | TAS | biological_process |
| GO:0050707 | Regulation of cytokine secretion | IEA | biological_process |
| GO:0051607 | Defense response to virus | IEA | biological_process |
| GO:0055089 | Fatty acid homeostasis | IEA | biological_process |
| GO:0055091 | Phospholipid homeostasis | IEA | biological_process |
| GO:0070236 | Negative regulation of activation-induced cell death of T cells | IEA | biological_process |
| GO:0070970 | Interleukin-2 secretion | IEA | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7442293264 | 0.0348629041 | 0.9999902473 | 0.3532049654 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3531401687 |
| GSE13712_SHEAR | Down | -0.0620370996 |
| GSE13712_STATIC | Down | -0.1513623190 |
| GSE19018 | Down | -0.3841979253 |
| GSE19899_A1 | Down | -0.1827214398 |
| GSE19899_A2 | Down | -0.9458470278 |
| PubMed_21979375_A1 | Up | 0.3489838976 |
| PubMed_21979375_A2 | Up | 0.4404500309 |
| GSE35957 | Up | 1.1196135177 |
| GSE36640 | Down | -0.4298498481 |
| GSE54402 | Up | 0.0564208122 |
| GSE9593 | Down | -1.1294925512 |
| GSE43922 | Up | 0.0856799457 |
| GSE24585 | Down | -0.2508005015 |
| GSE37065 | Down | -0.3748927653 |
| GSE28863_A1 | Down | -0.1460438660 |
| GSE28863_A2 | Up | 0.1808986309 |
| GSE28863_A3 | Down | -0.5696958649 |
| GSE28863_A4 | Down | -0.0215070867 |
| GSE48662 | Up | 0.0146850435 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT001462 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT020743 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-128-3p | MIMAT0000424 | MIRT022016 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-101-3p | MIMAT0000099 | MIRT027339 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-27a-3p | MIMAT0000084 | MIRT028739 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030803 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-484 | MIMAT0002174 | MIRT042048 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
