HCSGD entry for RNF213
1. General information
| Official gene symbol | RNF213 |
|---|---|
| Entrez ID | 57674 |
| Gene full name | ring finger protein 213 |
| Other gene symbols | ALO17 C17orf27 KIAA1618 MYMY2 MYSTR NET57 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0004842 | Ubiquitin-protein ligase activity | IDA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006200 | ATP catabolic process | IDA | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016567 | Protein ubiquitination | IDA | biological_process |
| GO:0016887 | ATPase activity | IDA | molecular_function |
| GO:0017111 | Nucleoside-triphosphatase activity | IEA | molecular_function |
| GO:0051865 | Protein autoubiquitination | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0085366399 | 0.7459379127 | 0.2370178270 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0447905135 |
| GSE13712_SHEAR | Up | 2.5962741358 |
| GSE13712_STATIC | Up | 1.8185363183 |
| GSE19018 | Up | 0.0362913950 |
| GSE19899_A1 | Down | -0.0550493592 |
| GSE19899_A2 | Down | -0.1319074928 |
| PubMed_21979375_A1 | Down | -0.4640935084 |
| PubMed_21979375_A2 | Down | -0.0520700859 |
| GSE35957 | Down | -0.7966192561 |
| GSE36640 | Up | 0.3345009249 |
| GSE54402 | Down | -0.0111263683 |
| GSE9593 | Up | 0.0244982097 |
| GSE43922 | Up | 0.0042915817 |
| GSE24585 | Up | 0.2730435826 |
| GSE37065 | Up | 0.5639499500 |
| GSE28863_A1 | Up | 1.6151728774 |
| GSE28863_A2 | Up | 1.6691230393 |
| GSE28863_A3 | Down | -0.0003063365 |
| GSE28863_A4 | Down | -0.0286292368 |
| GSE48662 | Down | -0.0705704606 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT005280 | pSILAC | Functional MTI (Weak) | 18668040 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT016943 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-423-3p | MIMAT0001340 | MIRT042649 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-99b-5p | MIMAT0000689 | MIRT044202 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047742 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
