HCSGD entry for SH3RF1
1. General information
| Official gene symbol | SH3RF1 |
|---|---|
| Entrez ID | 57630 |
| Gene full name | SH3 domain containing ring finger 1 |
| Other gene symbols | POSH RNF142 SH3MD2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005794 | Golgi apparatus | IEA | cellular_component |
| GO:0005829 | Cytosol | IDA | cellular_component |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016567 | Protein ubiquitination | IEA | biological_process |
| GO:0016874 | Ligase activity | IEA | molecular_function |
| GO:0030027 | Lamellipodium | IEA | cellular_component |
| GO:0043066 | Negative regulation of apoptotic process | IMP | biological_process |
| GO:0043154 | Negative regulation of cysteine-type endopeptidase activity involved in apoptotic process | IMP | biological_process |
| GO:0046328 | Regulation of JNK cascade | IEA | biological_process |
| GO:0048471 | Perinuclear region of cytoplasm | IEA | cellular_component |
| GO:2001237 | Negative regulation of extrinsic apoptotic signaling pathway | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8556040006 | 0.0321892443 | 0.9999902473 | 0.3376855719 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.4302762182 |
| GSE13712_SHEAR | Down | -0.2279656885 |
| GSE13712_STATIC | Down | -0.1448957051 |
| GSE19018 | Down | -0.0576651039 |
| GSE19899_A1 | Down | -0.7459882950 |
| GSE19899_A2 | Down | -0.0671060655 |
| PubMed_21979375_A1 | Down | -0.5856737006 |
| PubMed_21979375_A2 | Down | -0.1076484476 |
| GSE35957 | Up | 0.6868898283 |
| GSE36640 | Up | 0.4731553911 |
| GSE54402 | Down | -0.0346112198 |
| GSE9593 | Up | 0.6149905425 |
| GSE43922 | Down | -0.6676956311 |
| GSE24585 | Down | -0.0288149702 |
| GSE37065 | Down | -0.4051172517 |
| GSE28863_A1 | Down | -0.3801724174 |
| GSE28863_A2 | Up | 0.1220359208 |
| GSE28863_A3 | Down | -0.5394051424 |
| GSE28863_A4 | Down | -0.2274712186 |
| GSE48662 | Up | 0.0936253624 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-128-3p | MIMAT0000424 | MIRT021985 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-296-3p | MIMAT0004679 | MIRT038416 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
