HCSGD entry for KLHL1
1. General information
| Official gene symbol | KLHL1 |
|---|---|
| Entrez ID | 57626 |
| Gene full name | kelch-like family member 1 |
| Other gene symbols | MRP2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003779 | Actin binding | NAS | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005856 | Cytoskeleton | IEA | cellular_component |
| GO:0007628 | Adult walking behavior | IEA | biological_process |
| GO:0016358 | Dendrite development | IEA | biological_process |
| GO:0021680 | Cerebellar Purkinje cell layer development | IEA | biological_process |
| GO:0030036 | Actin cytoskeleton organization | NAS | biological_process |
| GO:0030425 | Dendrite | IEA | cellular_component |
| GO:0043025 | Neuronal cell body | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8201494282 | 0.6464078227 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1249075574 |
| GSE13712_SHEAR | Down | -0.1104076476 |
| GSE13712_STATIC | Down | -0.1754977764 |
| GSE19018 | Up | 0.0361270400 |
| GSE19899_A1 | Up | 0.1580239903 |
| GSE19899_A2 | Down | -0.0183947873 |
| PubMed_21979375_A1 | Down | -0.1956598193 |
| PubMed_21979375_A2 | Up | 0.0325676661 |
| GSE35957 | Up | 0.0065762382 |
| GSE36640 | Up | 0.0731596376 |
| GSE54402 | Up | 0.0291635813 |
| GSE9593 | Up | 0.1517036249 |
| GSE43922 | Up | 0.0177123044 |
| GSE24585 | Down | -0.3650475681 |
| GSE37065 | Up | 0.0155172528 |
| GSE28863_A1 | Down | -0.0134305752 |
| GSE28863_A2 | Down | -0.0068573958 |
| GSE28863_A3 | Up | 0.0517655180 |
| GSE28863_A4 | Down | -0.0253181388 |
| GSE48662 | Up | 0.0153829805 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017546 | Microarray | Functional MTI (Weak) | 18185580 |
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