HCSGD entry for KLHL1


1. General information

Official gene symbolKLHL1
Entrez ID57626
Gene full namekelch-like family member 1
Other gene symbolsMRP2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003779Actin bindingNASmolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005856CytoskeletonIEAcellular_component
GO:0007628Adult walking behaviorIEAbiological_process
GO:0016358Dendrite developmentIEAbiological_process
GO:0021680Cerebellar Purkinje cell layer developmentIEAbiological_process
GO:0030036Actin cytoskeleton organizationNASbiological_process
GO:0030425DendriteIEAcellular_component
GO:0043025Neuronal cell bodyIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.82014942820.64640782270.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1249075574
GSE13712_SHEARDown-0.1104076476
GSE13712_STATICDown-0.1754977764
GSE19018Up0.0361270400
GSE19899_A1Up0.1580239903
GSE19899_A2Down-0.0183947873
PubMed_21979375_A1Down-0.1956598193
PubMed_21979375_A2Up0.0325676661
GSE35957Up0.0065762382
GSE36640Up0.0731596376
GSE54402Up0.0291635813
GSE9593Up0.1517036249
GSE43922Up0.0177123044
GSE24585Down-0.3650475681
GSE37065Up0.0155172528
GSE28863_A1Down-0.0134305752
GSE28863_A2Down-0.0068573958
GSE28863_A3Up0.0517655180
GSE28863_A4Down-0.0253181388
GSE48662Up0.0153829805

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017546MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.