HCSGD entry for SHROOM3

1. General information

Official gene symbolSHROOM3
Entrez ID57619
Gene full nameshroom family member 3
Other gene symbolsAPXL3 SHRM ShrmL
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000902Cell morphogenesisISSbiological_process
GO:0001843Neural tube closureIEAbiological_process
GO:0002066Columnar/cuboidal epithelial cell developmentIEAbiological_process
GO:0003779Actin bindingIEAmolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0005856CytoskeletonISScellular_component
GO:0005874MicrotubuleIEAcellular_component
GO:0005912Adherens junctionISScellular_component
GO:0007389Pattern specification processISSbiological_process
GO:0008360Regulation of cell shapeIEAbiological_process
GO:0016324Apical plasma membraneISScellular_component
GO:0030036Actin cytoskeleton organizationIEAbiological_process
GO:0043296Apical junction complexISScellular_component
GO:0043482Cellular pigment accumulationISSbiological_process
GO:0045176Apical protein localizationISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.86531298580.00063860040.99999024730.0470268156

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-1.1673716768
GSE13712_SHEARUp1.0763012113
GSE13712_STATICUp0.6036924000
GSE19018Up0.0096856066
GSE19899_A1Down-2.2678181613
GSE19899_A2Down-1.3696943505
PubMed_21979375_A1Down-3.3702714504
PubMed_21979375_A2Down-2.2745089231
GSE35957Up0.4635766290
GSE36640Down-0.7394626913
GSE54402Down-1.4425756743
GSE9593Up0.5445746782
GSE43922Down-1.7547422833
GSE24585Down-0.1403143370
GSE37065Down-0.3787717950
GSE28863_A1Up0.0973329590
GSE28863_A2Down-0.2698673092
GSE28863_A3Down-0.4899039120
GSE28863_A4Down-0.1270878508
GSE48662Down-0.1137372167

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT019043MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.