HCSGD entry for MARCH4
1. General information
| Official gene symbol | MARCH4 |
|---|---|
| Entrez ID | 57574 |
| Gene full name | membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase |
| Other gene symbols | MARCH-IV RNF174 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | IEA | cellular_component |
| GO:0004842 | Ubiquitin-protein ligase activity | IDA | molecular_function |
| GO:0005795 | Golgi stack | IDA | cellular_component |
| GO:0005802 | Trans-Golgi network | IDA | cellular_component |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0209250712 | 0.2099127503 | 0.3488982301 | 0.8850990710 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0078691876 |
| GSE13712_SHEAR | Up | 2.4053520081 |
| GSE13712_STATIC | Up | 1.4115754688 |
| GSE19018 | Up | 0.2990640908 |
| GSE19899_A1 | Down | -0.3498220201 |
| GSE19899_A2 | Up | 0.0652677193 |
| PubMed_21979375_A1 | Up | 1.3574481466 |
| PubMed_21979375_A2 | Up | 0.6884842840 |
| GSE35957 | Up | 1.0269214749 |
| GSE36640 | Up | 0.9731237721 |
| GSE54402 | Down | -0.3377121395 |
| GSE9593 | Down | -0.0614881713 |
| GSE43922 | Down | -0.0865213565 |
| GSE24585 | Down | -0.0368550641 |
| GSE37065 | Down | -0.2381321206 |
| GSE28863_A1 | Down | -0.7036281470 |
| GSE28863_A2 | Down | -0.2841343193 |
| GSE28863_A3 | Up | 0.0140645598 |
| GSE28863_A4 | Down | -0.0715552545 |
| GSE48662 | Down | -0.0724828558 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-373-3p | MIMAT0000726 | MIRT004073 | Microarray | Functional MTI (Weak) | 15685193 |
| hsa-miR-320a | MIMAT0000510 | MIRT044444 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
