HCSGD entry for KLHL8
1. General information
| Official gene symbol | KLHL8 |
|---|---|
| Entrez ID | 57563 |
| Gene full name | kelch-like family member 8 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0016567 | Protein ubiquitination | IDA | biological_process |
| GO:0031463 | Cul3-RING ubiquitin ligase complex | IDA | cellular_component |
| GO:0042787 | Protein ubiquitination involved in ubiquitin-dependent protein catabolic process | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4895278561 | 0.4222394286 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1403915392 |
| GSE13712_SHEAR | Down | -0.0111976461 |
| GSE13712_STATIC | Down | -0.0490302055 |
| GSE19018 | Down | -0.5866878275 |
| GSE19899_A1 | Down | -0.1937171437 |
| GSE19899_A2 | Up | 0.0949559409 |
| PubMed_21979375_A1 | Up | 0.4665445862 |
| PubMed_21979375_A2 | Up | 0.1400181912 |
| GSE35957 | Down | -0.0338777654 |
| GSE36640 | Up | 0.2616389699 |
| GSE54402 | Up | 0.0215382133 |
| GSE9593 | Down | -0.1093988028 |
| GSE43922 | Up | 0.1162225098 |
| GSE24585 | Up | 0.0903229790 |
| GSE37065 | Up | 0.1016630182 |
| GSE28863_A1 | Up | 0.2852336156 |
| GSE28863_A2 | Down | -0.0547323537 |
| GSE28863_A3 | Down | -0.5895856065 |
| GSE28863_A4 | Down | -0.2662361811 |
| GSE48662 | Up | 0.3484318204 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024647 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026842 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040093 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-221-3p | MIMAT0000278 | MIRT046891 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
